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首页|期刊导航|International Journal of Oral Science|Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC

Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC

Lixuan Wang Rongchun Yang Yue Kong Jing Zhou Yingyao Chen Rui Li Chuwen Chen Xinran Tang Xiaobing Chen Juan Xia Xijuan Chen Bin Cheng Xianyue Ren

International Journal of Oral Science2024,Vol.16Issue(4):P.711-727,17.
International Journal of Oral Science2024,Vol.16Issue(4):P.711-727,17.DOI:10.1038/s41368-024-00310-2

Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC

Lixuan Wang 1Rongchun Yang 1Yue Kong 1Jing Zhou 1Yingyao Chen 1Rui Li 2Chuwen Chen 1Xinran Tang 2Xiaobing Chen 1Juan Xia 1Xijuan Chen 1Bin Cheng 1Xianyue Ren1

作者信息

  • 1. Hospital of Stomatology,Sun Yat-Sen University,Guangzhou,China Guangdong Provincial Key Laboratory of Stomatology,Guangzhou,China Guanghua School of Stomatology,Sun Yat-Sen University,Guangzhou,China
  • 2. Department of Radiation Oncology,Nanfang Hospital,Southern Medical University,Guangzhou,China
  • 折叠

摘要

关键词

metabolism/therapeutic/precise

分类

医药卫生

引用本文复制引用

Lixuan Wang,Rongchun Yang,Yue Kong,Jing Zhou,Yingyao Chen,Rui Li,Chuwen Chen,Xinran Tang,Xiaobing Chen,Juan Xia,Xijuan Chen,Bin Cheng,Xianyue Ren..Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC[J].International Journal of Oral Science,2024,16(4):P.711-727,17.

基金项目

supported by grants from the GuangDong Basic and Applied Basic Research Foundation(No.2023A1515030121,No.2021A1515111020,No.2023A1515010246) (No.2023A1515030121,No.2021A1515111020,No.2023A1515010246)

the National Natural Science Foundation of China(No.82273148,No.82103555,No.82301086) (No.82273148,No.82103555,No.82301086)

the Science and Technology Projects in Guangzhou(No.202206080009)。 (No.202206080009)

International Journal of Oral Science

OACSTPCD

1674-2818

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