法医学杂志2024，Vol.40Issue(6)：589-596,607,9.DOI:10.12116/j.issn.1004-5619.2023.231203
MRI在华东地区汉族男性青少年手腕骨骺发育的量化及骨龄评估中的应用
MRI Application in Quantification of Epiphyseal Development in the Wrist and Bone Age Estimation of Han Male Adolescents in East China
周智露 1万雷 2张东飞 3陈捷敏 2王亚辉 2郝虹霞 2刘太昂 4何宇亨 4龙定念 5刘瑞珏2
作者信息
- 1. 贵州医科大学法医学院,贵州 贵阳 550009
- 2. 司法鉴定科学研究院 上海市法医学重点实验室 司法部司法鉴定重点实验室 上海市司法鉴定专业技术服务平台,上海 200063
- 3. 安徽天衡司法鉴定所,安徽 阜阳 236000
- 4. 上海数之微信息科技有限公司,上海 200444
- 5. 广西金桂司法鉴定中心,南宁 广西 530000
- 折叠
摘要
Abstract
Objective To investigate the value of wrist MRI in bone age estimation for male adoles-cents in Shanghai,Zhejiang and Jiangsu.Methods A total of 124 Han male adolescents aged 6.0 to 18.0 years from Shanghai,Zhejiang and Jiangsu were selected as subjects.Their weight and height were measured,and T1WI and T2WI sequences of the wrist were scanned.The distal ends of the ra-dius and ulna,and the first to five metacarpal epiphyses and corresponding metaphyses were selected as observational indexes after MRI images of the wrist were obtained.The development of each index was classified(0-2 grades)by a deputy senior imaging expert,then the maximum width of each in-dex was measured by another deputy senior expert.Height,weight,classification and maximum width of indexes were used as input variables,and age was used as the target variable.Support vector ma-chine,random forest,current reality tree,and linear regression models were established to estimate the bone age,and the model with the highest accuracy was selected.Results The height,weight,classifica-tion of wrist bone epiphysis development,maximum width of each bone metaphysis and epiphysis were all correlated with age(P<0.05).The accuracies of the support vector machine were the highest when the differences between bone age and actual chronological age were within 1.0 and 1.5 years(88.7%and 96.0%,respectively).Conclusion It is feasible to estimate bone age by using MRI images.Quantifying the maximum width of the epiphysis and corresponding metaphysis of bone and combining it with MRI image classification can effectively reduce the estimation error.关键词
法医人类学/年龄推断/磁共振成像/手腕部/骨骺/骨发育分级/机器学习/青少年Key words
forensic anthropology/age estimation/magnetic resonance imaging(MRI)/wrist/epiphy-sis/stage of skeletal growth/machine learning/adolescents分类
医药卫生引用本文复制引用
周智露,万雷,张东飞,陈捷敏,王亚辉,郝虹霞,刘太昂,何宇亨,龙定念,刘瑞珏..MRI在华东地区汉族男性青少年手腕骨骺发育的量化及骨龄评估中的应用[J].法医学杂志,2024,40(6):589-596,607,9.
