UCH-L1、Lp-PLA2、Hcy与ACI患者颈动脉斑块形成的关系及联合检测价值OACSTPCD
Relationship between UCH-L1,Lp-PLA2,and Homocysteine levels and carotid plaque formation,and the value of their combined detection in patients with acute cerebral infarction
目的:急性脑梗死(acute cerebral infarction,ACI)患者短期预后不良率高达41%,故早期预测ACI短期预后对临床治疗方案的调整及出院后干预方案的制订至关重要.而颈动脉斑块是颈动脉粥样硬化的重要表现,且易继发血栓,导致管腔狭窄,现被证实可参与ACI发病及预后,探讨颈动脉斑块形成影响因素对早期识别及防治ACI、改善预后十分重要.基于此,本研究探讨血清泛素羧基末端水解酶L1(ubiquitin carboxyl termina…查看全部>>
Objective:The short-term poor prognosis rate in acute cerebral infarction(ACI)patients is as high as 41%,making early prediction of short-term outcomes crucial for tailoring clinical treatments and post-discharge interventions.Carotid plaque formation,a key manifestation of carotid atherosclerosis,is prone to thrombosis and subsequent luminal narrowing,and has been confirmed to contribute to the pathogenesis and prognosis of ACI.This study investigates the a…查看全部>>
王琳;李影;杨海华;赵性泉
首都医科大学大兴教学医院神经内科,北京 102600||首都医科大学附属北京天坛医院神经内科,北京 100070首都医科大学大兴教学医院神经内科,北京 102600首都医科大学大兴教学医院神经内科,北京 102600首都医科大学附属北京天坛医院神经内科,北京 100070||首都医科大学中国神经疾病临床研究中心,北京 100070||中国医学科学院脑血管病人工智能研究中心,北京 100010
急性脑梗死颈动脉斑块短期预后泛素羧基末端水解酶L1同型半胱氨酸脂蛋白相关磷脂酶A2
acute cerebral infarctioncarotid plaqueshort-term prognosisubiquitin carboxyl-terminal hydrolase L1homocysteinelipoprotein-associated phospholipase A2
《临床与病理杂志》 2024 (10)
1368-1377,10
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