神经损伤与功能重建2025，Vol.20Issue(2)：90-92,101,4.DOI:10.16780/j.cnki.sjssgncj.20240026
自噬在神经退行性疾病发病机制及治疗中的作用
The Role of Autophagy in the Pathogenesis and Treatment of Neurodegenerative Diseases
廖冬仪 1孙玉林 1石界梅 1李双阳 1白雪1
作者信息
- 1. 西南医科大学附属中医医院 四川泸州 646000
- 折叠
摘要
Abstract
Autophagy is a self-degradation process of cells that plays an important role in clearing misfolded or aggregated proteins,removing damaged organelles(such as mitochondria,endoplasmic reticulum,and peroxi-somes),and eliminating intracellular pathogens.This article reviews and analyzes the relationship between au-tophagy and neurodegenerative diseases(Alzheimer's disease,Parkinson's disease,Huntington's disease,and amyotrophic lateral sclerosis)by reviewing relevant literature,aiming to summarize the role of autophagy in the pathogenesis and treatment of neurodegenerative diseases,providing new ideas for the treatment of neurodegen-erative disorders.关键词
细胞自噬/神经退行性疾病/阿尔兹海默病/帕金森病/亨廷顿病/肌萎缩侧索硬化/治疗Key words
cellular autophagy/neurodegenerative diseases/Alzheimer's disease/Parkinson's disease/Hun-tington's disease/multiple sclerosis mechanism/therapy分类
临床医学引用本文复制引用
廖冬仪,孙玉林,石界梅,李双阳,白雪..自噬在神经退行性疾病发病机制及治疗中的作用[J].神经损伤与功能重建,2025,20(2):90-92,101,4.
