摘要
Abstract
OBJECTIVE To explore the relationship between cervical lymph node metastasis of thyroid cancer and ultrasound features,as well as BRAF V600E mutation.METHODS A retrospective study was conducted on 120 patients admitted to the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China between October 2022 and March 2023 to analyze the relationship between neck lymph node metastasis,ultrasound features,and BRAF V600E mutation.RESULTS A total of 120 thyroid cancer patients were included,with a lymph node metastasis rate of 60.00%(72/120)and a BRAF V600E mutation rate of 79.17%.There was no statistically significant difference between different BRAF V600E mutations and cervical lymph node metastasis(χ2=1.895,P=0.169).More than 1 aspect ratio,multiple lesions,calcification,rich blood flow,and lesion diameter≥1 cm are risk factors for lymph node metastasis(OR=3.448,P=0.009;OR=3.758,P=0.008;OR=2.834,P=0.047;OR=3.552,P=0.024;OR=3.521,P=0.031),Age>40 years old is a protective factor for lymph node metastasis(OR=0.357,P=0.024).CONCLUSION For papillary thyroid carcinoma patients aged≤40 years,with ultrasound findings of aspect ratio>1,multiple lesions,lesion diameter≥1 cm,calcification,and abundant blood flow,special attention should be paid to lymph node metastasis,appropriate treatment methods should be selected,and a reasonable lymph node dissection range should be formulated.关键词
甲状腺肿瘤/乳头状甲状腺癌/淋巴结转移/影响因素Key words
Thyroid Neoplasms/Thyroid Cancer,Papillary/lymph node metastasis/influence factor
