黑龙江动物繁殖2025，Vol.33Issue(1)：31-36,6.DOI:10.19848/j.cnki.ISSN1005-2739.2025.02.0006
孕酮调控奶牛胚胎附植的研究进展
Progress in progesterone regulation of embryo attachment in dairy cows
摘要
Abstract
One of the major challenges facing modern dairy cow husbandry is low pregnancy rates,a major contributing factor of which is believed to be due to progesterone(P4)deficiency.P4,secreted by the corpus luteum,is an essential hormone for the maintenance of pregnancy and plays a crucial role in embryo attachment and development.To improve pregnancy rates in dairy cows,researchers have proposed several strategies to regulate P4 levels,including such techniques as supplementing exogenous P4 and utilizing gonadotropin-releasing hormone(GnRH)and human chorionic gonadotropin(hCG)to promote endogenous P4 synthesis.This paper reviewed the mechanism of P4 regulation in the early embryonic development,endometrial receptivity and maternal immune tolerance and other embryo attachment-related processes in dairy cows,and explored the effects of different P4 regulation techniques on the pregnancy rate of dairy cows,aiming to provide a reference for the research and application of embryo attachment techniques based on the regulation of P4 in improving the reproductive efficiency of dairy cows,reducing the cost of breeding and promoting the sustainable development of the dairy industry.关键词
奶牛/妊娠率/孕酮(P4)/胚胎附植/免疫耐受/促性腺激素释放激素(GnRH)/人绒毛膜促性腺激素(hCG)Key words
dairy cow/pregnancy rates/progesterone(P4)/embryonic attachment/immune tolerance/gonadotropin-releasing hormone(GnRH)/human chorionic gonadotropin(hCG)分类
农业科技引用本文复制引用
王红战,РЮМИН Иван Андреевич,ТАНЫГИНА Анастасия Игоревна,刘士铖,李博,郑鹏..孕酮调控奶牛胚胎附植的研究进展[J].黑龙江动物繁殖,2025,33(1):31-36,6.基金项目
"十四五"国家重点研发计划项目(2023YFD1300602) （2023YFD1300602）
