两种术式治疗膝骨关节炎的疗效比较OA

Objective To compare the efficacy of unicondylar knee arthroplasty(UKA)and total knee arthroplasty(TKA)in the treatment of knee osteoarthritis(KOA)and the surgical collateral injuries.Methods The 47 patients with KOA were divided into UKA group(21 cases were treated with UKA)and TKA group(26 cases were treated with TKA).The clinical observation indicators were compared between two groups,and the surgical collateral injuries were compared through the blood indicators.Results All patients were followed up for 18～27(22.79±3.01)months.①There were no statistical differences between the two groups in the operation time and the knee flexion range of motion(ROM)at 1 week and 1 month postoperation(P>0.05);postoperative drainage volume and knee flexion ROM in UKA group were both better than those in TKA group(P<0.05).At the last follow-up,the knee joint of the two groups could move freely without pain,and the patients could walk freely with full weight-bearing,and the gaint was normal.② White blood cell count:there was no statistical difference between the two groups before operation and at the 1,4,7 d after operation(P>0.05).The neutrophil count and neutrophil percentage:At 7 d after operation,UKA group were lower than those in TKA group(P<0.05);two groups had no statistical differences before operation and at 1,4 d after operation(P>0.05).Hypersensitive C-reactive protein:UKA group was smaller than TKA group on the first day after operation(P<0.05),and there was no statistical difference between the two groups before operation and at 4,7 d after operation(P>0.05).In further analysis with repeated measures variance including grouping factors,there was an interaction between the two surgical approaches and the time factor in neutrophil percentage change(P<0.05).Conclusions Compared with TKA,the surgical collateral injuries is less in the UKA causes,and which has better clinical efficacy.