临床骨科杂志2025，Vol.28Issue(1)：46-50,5.DOI:10.3969/j.issn.1008-0287.2025.01.016
两种术式治疗膝骨关节炎的疗效比较
Effect comparison of two surgical procedures in the treatment of knee osteoarthritis
陈宾 1王跃辉 1周宇 1陈明伟 1陈文忠 1司文腾1
作者信息
- 1. 郑州市骨科医院关节病科,河南 郑州 450052
- 折叠
摘要
Abstract
Objective To compare the efficacy of unicondylar knee arthroplasty(UKA)and total knee arthroplasty(TKA)in the treatment of knee osteoarthritis(KOA)and the surgical collateral injuries.Methods The 47 patients with KOA were divided into UKA group(21 cases were treated with UKA)and TKA group(26 cases were treated with TKA).The clinical observation indicators were compared between two groups,and the surgical collateral injuries were compared through the blood indicators.Results All patients were followed up for 18～27(22.79±3.01)months.①There were no statistical differences between the two groups in the operation time and the knee flexion range of motion(ROM)at 1 week and 1 month postoperation(P>0.05);postoperative drainage volume and knee flexion ROM in UKA group were both better than those in TKA group(P<0.05).At the last follow-up,the knee joint of the two groups could move freely without pain,and the patients could walk freely with full weight-bearing,and the gaint was normal.② White blood cell count:there was no statistical difference between the two groups before operation and at the 1,4,7 d after operation(P>0.05).The neutrophil count and neutrophil percentage:At 7 d after operation,UKA group were lower than those in TKA group(P<0.05);two groups had no statistical differences before operation and at 1,4 d after operation(P>0.05).Hypersensitive C-reactive protein:UKA group was smaller than TKA group on the first day after operation(P<0.05),and there was no statistical difference between the two groups before operation and at 4,7 d after operation(P>0.05).In further analysis with repeated measures variance including grouping factors,there was an interaction between the two surgical approaches and the time factor in neutrophil percentage change(P<0.05).Conclusions Compared with TKA,the surgical collateral injuries is less in the UKA causes,and which has better clinical efficacy.关键词
单间室膝骨关节炎/膝关节单髁置换术/全膝关节置换术/白细胞计数/中性粒细胞/超敏C-反应蛋白Key words
unicompartmental knee osteoarthritis/unicondylar knee arthroplasty/total knee arthroplasty/white blood cell count/neutrophil/hypersensitive C-reactive protein分类
临床医学引用本文复制引用
陈宾,王跃辉,周宇,陈明伟,陈文忠,司文腾..两种术式治疗膝骨关节炎的疗效比较[J].临床骨科杂志,2025,28(1):46-50,5.
