护理学报2025，Vol.32Issue(4)：59-63,5.DOI:10.16460/j.issn1008-9969.2025.04.059
腹腔热灌注化疗患者术中实施不同目标体温管理的效果观察
Effect of target temperature management strategy on intraoperative temperature management in patients undergoing hyperthermic intraperitoneal chemotherapy
摘要
Abstract
Objective To observe the effect of temperature management strategy based on different target temperatures on intraoperative temperature management in patients undergoing hyperthermic intraperitoneal chemotherapy(HIPEC).Methods A total of 120 patients with colorectal cancer who underwent HIPEC in the operation center of a tertiary grade-A general hospital in Tianjin from January 2022 to December 2023 were selected and randomly divided into control group(n=60)and observation group(n=60)according to chronological order.Patients in the control group were treated with traditional temperature management,ad those in the observation group with temperature management strategy based on different target temperatures.Bladder and esophageal temperatures before HIPEC(T1),15 min after the beginning(T2),30 min after the beginning(T3),45 min after the beginning(T4)and at the end of HIPEC(T5)were observed in the two groups,and the incidence of perioperative adverse events such as moderate to severe hyperthermia,reduction of blood pressure,metabolic acidosis,arrhythmia and postoperative shivering was compared between the two groups.The patients were followed up 3 months after the treatment to observe the differences in postoperative survival and tumor recurrence.Results During HIPEC,esophageal temperature in the observation group was significantly lower than that in the control group at T3-T5,showing statistical significance(P<0.05).Compared with that in the control group,the incidence of moderate to severe hyperthermia,reduction of blood pressure,metabolic acidosis,arrhythmia and postoperative shivering in observation group was significantly lower(P<0.05),showing statistical significance.Conclusion Intraoperative temperature management strategy based on different target temperatures in patients undergoing HIPEC can effectively prevent excessive increase of core temperature and reduce the incidence of perioperative high fever and related complications.关键词
结直肠肿瘤/腹膜转移/腹腔热灌注化疗/体温管理/围手术期护理Key words
colorectal neoplasms/peritoneal metastasis/hyperthermic intraperitoneal chemotherapy/body temperature/perioperative nursing分类
临床医学引用本文复制引用
刘璐,朱钰,曹义,张华,彭玉娜..腹腔热灌注化疗患者术中实施不同目标体温管理的效果观察[J].护理学报,2025,32(4):59-63,5.基金项目
天津市医学重点学科(专科)建设项目(TJYXZDXK-045A) （专科）
