摘要
Abstract
Objective:To investigate the therapeutic effect of laparoscopically gastric perforation repair in patients with acute gastric ulcer perforation.Methods:The clinical data of 61 patients with acute gastric ulcer perforation admitted to Zibo Municipal Hospital from March 2015 to February 2024 were retrospectively analyzed,and they were divided into a control group(n=30)and a study group(n=31)according to different surgical methods.The control group underwent traditional open perforation repair surgery,while the study group underwent laparoscopically gastric perforation repair surgery.Both groups were observed until 2 days after surgery.The clinical related indicators,stress response indicators,pepsinogen,and the occurrence of complications were compared between the two groups.Results:The operation time,hospital stay,and drainage tube removal time of the study group were shorter than those of the control group;the intraoperative blood loss of the study group was less than that of the control group,the differences were statistically significant(P<0.05).Two days after surgery,the levels of tumor necrosis factor-α,interleukin-6 and C-reactive protein in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).Two days after surgery,the levels of pepsinogen Ⅰ and pepsinogen Ⅱ in the study group were lower than those in the control group,with statistical significance(P<0.05).The incidence of complications in the study group was 3.23%,which was lower than 26.57%in the control group,the difference was statistically significant(P<0.05).Conclusion:Laparoscopically gastric perforation repair in patients with acute gastric ulcer perforation can improve clinical and pepsinogen indexes,reduce stress response indexes,and lower the incidence of complications,which is conducive to postoperative recovery of patients.关键词
胃溃疡穿孔/腹腔镜/胃穿孔修补术/胃蛋白酶原Key words
Gastric ulcer perforation/Laparoscopic/Gastric perforation repair/Pepsinogen分类
医药卫生
