四川精神卫生2025，Vol.38Issue(1)：14-21,8.DOI:10.11886/scjsws20240303001
目标特征对抑郁障碍患者前瞻记忆的影响
Effect of target characteristics on prospective memory in patients with depressive disorder
摘要
Abstract
Background Many studies have shown that patients with depressive disorder show impairments in prospective memory,while it is deemed necessary for facilitating their social reintegration,and the current research findings are inconsistent regarding the factors affecting prospective memory of patients with depressive disorder.Objective To explore the impact of target characteristics(emotional valence and salience)on prospective memory in patients with depressive disorder,so as to provide references for the training and recovery of prospective memory function in these patients.Methods From January to December 2022,53 patients with depressive disorder were recruited from the outpatient department of Inner Mongolia Autonomous Mental Health Center.Meanwhile,45 healthy individuals were concurrently recruited from surrounding communities as control group.An experiment with a 2(participant type:depressive disorder,healthy control)×2(target salience:salient,non-salient)×3(emotional valence:positive,neutral,negative)factorial design was conducted.The positive/neutral/negative emotional pictures from Chinese Affective Picture System(CAPS)were used for emotional stimulation.A dual-task experimental paradigm was adopted,and the response time and accuracy in prospective memory task and ongoing task were recorded for participants with different target characteristics.Results ①In the prospective memory task,the main effect of participant type was statistically significant,with the depressive group showing lower accuracy(F=14.892,P<0.01)and longer response time(F=10.642,P=0.002)compared with control group.② The main effect of target emotional valence on accuracy(F=7.575,P=0.001)and response time(F=3.196,P=0.044)in the prospective memory task was statistically significant.Simple effect analysis revealed that depressive group yielded a shorter response time and higher accuracy rate under negative conditions compared with positive and neutral conditions(P<0.05 or 0.01).③ The main effect of target salience on accuracy(F=6.659,P=0.012)and response time(F=10.106,P=0.002)in the prospective memory task was also statistically significant,with higher accuracy and shorter response time for salient targets compared with non-salient targets.Conclusion Patients with depressive disorder demonstrate preferential attention to and processing of negative stimuli in prospective memory tasks,while increasing target salience may facilitate spontaneous processing of prospective memory task in patients with depressive disorder.关键词
抑郁障碍/前瞻记忆/目标情绪效价/目标凸显性Key words
Depressive disorder/Prospective memory/Target emotional valence/Target salience分类
临床医学引用本文复制引用
陈敏,吕东升,王峥,侯友..目标特征对抑郁障碍患者前瞻记忆的影响[J].四川精神卫生,2025,38(1):14-21,8.基金项目
内蒙古自治区卫生健康委医疗卫生科技计划项目(项目名称:抑郁障碍患者认知功能损害与睡眠紊乱关系的研究,项目编号:202202104) Inner Mongolia Health Commission Medical Health Science and Technology Project(number,202202104) （项目名称:抑郁障碍患者认知功能损害与睡眠紊乱关系的研究,项目编号:202202104）
