四川精神卫生2025，Vol.38Issue(1)：22-27,6.DOI:10.11886/scjsws20240614001
抑郁障碍患者的决策行为及其与抑郁焦虑症状的关系
Decision-making behavior in patients with depressive disorder and its relationship with depressive and anxiety symptoms
摘要
Abstract
Background Patients with depressive disorder often exhibit impaired decision-making functions.However,the relationship between decision-making abilities and depressive and anxiety symptoms in these patients remains unclear.Objective To explore the characteristics of decision-making behavior in patients with depressive disorder,and to analyze its relationship with clinical symptoms.Methods A total of 48 patients diagnosed with depressive disorder according to the Diagnostic and Statistical Manual of Mental Disorders,fourth edition(DSM-IV)were recruited from the Department of Psychosomatic Medicine of the Affiliated Hospital of Southwest Medical University from October 2020 to May 2023.Concurrently,52 healthy individuals matched for age and gender were recruited from Luzhou as the control group.Beck Depression Inventory(BDI)and Beck Anxiety Inventory(BAI)were used for assessment,and decision-making behavior was evaluated using Probabilistic Reversal Learning(PRL)task.Indicators assessed included the number of trials to criterion,perseverative errors,win-stay rate and lose-shift rate.Spearman correlation analysis was used to assess the correlation between BDI and BAI scores and PRL task indicators.Results The depression group showed a significantly higher lose-shift rate compared with the control group(t=3.684,P<0.01).There were no statistically significant differences between two groups in trials to criterion,perseverative errors and win-stay rate(t=0.329,0.132,0.609,P>0.05).In depression group,BDI and BAI scores were positively correlated with the win-stay rate(r=0.450,0.398,P<0.01).Conclusion Patients with depressive disorder are more likely to change their decision-making strategies following negative outcomes.Furthermore,the severity of depressive and anxiety symptoms is associated with a greater propensity to maintain existing decisions after receiving positive feedback.关键词
抑郁障碍/决策行为/概率翻转学习/抑郁焦虑症状Key words
Depressive disorder/Decision-making behavior/Probability reversal learning/Depressive and anxiety symptoms分类
临床医学引用本文复制引用
王昱翔,张罗雅,张毛毛,邓娟,彭彦杰,成晓彤,刘可智,雷威,陈晶..抑郁障碍患者的决策行为及其与抑郁焦虑症状的关系[J].四川精神卫生,2025,38(1):22-27,6.基金项目
2019年度泸州科技局-西南医科大学联合项目(项目名称:抑郁症目标导向-习惯学习系统异常及其神经机制,项目编号:2019LZXNYDJ39) 2019 Joint Project of Luzhou Science and Technology Bureau-Southwest Medical University(number,2019LZXNYDJ39 （项目名称:抑郁症目标导向-习惯学习系统异常及其神经机制,项目编号:2019LZXNYDJ39）
