实用医学杂志2025，Vol.41Issue(4)：459-464,6.DOI:10.3969/j.issn.1006-5725.2025.04.001
2024年美国胃肠病学院幽门螺杆菌感染治疗最新临床实践指南要点解读
Interpretation of ACG clinical practice guideline in 2024:treatment of helicobacter pylori infection
摘要
Abstract
Helicobacter pylori(H.pylori)infection is a prevalent global health issue that can lead to indiges-tion,peptic ulcer disease,and gastric cancer.With ongoing research advancements,significant progress has been made in the eradication of H.pylori.Based on these important findings from North America,the American College of Gastroenterology(ACG)has released updated clinical practice guideline(CPG),published in the American Journal of Gastroenterology in September 2024.Compared to previous guidelines,key updates include:increased resistance rates to critical antibiotics used for H.pylori treatment,such as clarithromycin and levofloxacin,which have reduced the efficacy of common treatment regimens containing these antibiotics;and research on novel treat-ment options for newly diagnosed patients,including new antibiotic alternatives(e.g.,rifampicin)or more potent next-generation gastric acid inhibitors(e.g.,potassium-competitive acid blockers,PCABs).These updates provide the latest evidence and reference for the clinical management of H.pylori infection.关键词
幽门螺杆菌/感染/管理/美国胃肠病学院/临床实践指南Key words
helicobacter pylori/infection/management/the American College of Gastroenterology/clinical practice guideline分类
临床医学引用本文复制引用
吴新国,郑汝桦,常新,牛春燕,张福玉..2024年美国胃肠病学院幽门螺杆菌感染治疗最新临床实践指南要点解读[J].实用医学杂志,2025,41(4):459-464,6.基金项目
江苏省医院协会医院管理创新研究课题(编号:JSYGY-3-2024-193) （编号:JSYGY-3-2024-193）
2022年度南京市卫生科技发展专项资金项目计划(编号:YKK22240) （编号:YKK22240）
南京大学中国医院改革发展研究院课题项目(编号:NDYG2023037) （编号:NDYG2023037）
