武警医学2025，Vol.36Issue(2)：154-158,5.
CT影像组学鉴别肾上腺富血供腺瘤和嗜铬细胞瘤
Value of CT radiomics in discrimination of hypervascular adrenal adenoma from pheo-chromocytoma
程远华 1陆静 2滑蓉蓉 2何绪成 2张亚楠 2王贵生 2陈晓霞2
作者信息
- 1. 636150,四川省宣汉县人民医院放射影像科
- 2. 100039 北京,解放军总医院第三医学中心放射诊断科
- 折叠
摘要
Abstract
Objective To explore the value of the CT radiomics model in the differential diagnosis of hypervascular adrenal adenoma(HAA)and pheochromocytoma(AP).Methods A total of 79 patients(53 HAA and 26 AP)who underwent phase 4 CT scan and were pathologically confirmed in the Department of Radiology of the Third Medical Center of PLA General Hospital from Janu-ary 2022 to July 2024 were retrospectively included.Clinical indicators and radiomics features extracted from CT images through scien-tific research platform were analyzed.Using the F_Test to reduce dimensionality and screen radiomics features,factors with statistically significant differences were included in binary logistic regression analysis and subsequent modeling.Finally,ROC curve and decision curve of the predictive model were plotted to evaluate its predictive performance and clinical application value.Results The value of plain CT scan(OR=1.166,P<0.01)and the long diameter of tumor(OR=2.226,P<0.01)were independent risk factors for the discrimination of the two groups.The AUC based on CTpre,arterial phase(CTa),late arterial phase(CTla),venous phase(CTv),four-phase combination,imaging features,and clinical indicator model validation set were 0.93,0.92,0.88,0.86,0.87,0.88 and 0.72,respectively.The CTpre-based radiomics model was characterized by the best performance,with accuracy,sensitivity,and spe-cificity of 0.86,0.89,and 0.85,respectively.Conclusions The model based om CT radiomics has good predictive performance and application value in the discrimination of HAA from AP.关键词
CT/影像组学/肾上腺富血供腺瘤/嗜铬细胞瘤/鉴别Key words
CT/radiomics/hypervascular adrenal adenoma/adrenal pheochromocytoma/discrimination分类
医药卫生引用本文复制引用
程远华,陆静,滑蓉蓉,何绪成,张亚楠,王贵生,陈晓霞..CT影像组学鉴别肾上腺富血供腺瘤和嗜铬细胞瘤[J].武警医学,2025,36(2):154-158,5.
