医疗卫生装备2025，Vol.46Issue(2)：63-67,5.DOI:10.19745/j.1003-8868.2025030
基于高分辨磁共振血管壁成像的症状性大脑中动脉粥样硬化斑块特征与脑卒中复发风险关系研究
Correlation of characteristics of symptomatic middle cerebral artery plaques with risk of stroke recurrence:Study based on high-resolution vessel wall imaging
摘要
Abstract
Objective To investigate the correlation of the characteristics of symptomatic middle cerebral artery plaques with the risk of stroke recurrence based on high-resolution vessel wall imaging(HR-VWI).Methods Totally 83 patients hospitalized for acute ischemic stroke(AIS)and transient ischemic attack(TIA)at Jingmen People's Hospital and Yichang Central People's Hospital from January 2019 to August 2022 were selected prospectively,who all underwent the treatment with antiplatelet aggregation and intensive lipid lowering by statins.During the follow-up,AIS or TIA recurrences were determined in case of newly found symptoms of neurological impairment in the same supply area of the responsible vessel or new infarct foci confirmed by cranial diffusion weighted imaging(DWI).The patients with AIS or TIA recurrences were enrolled into a recurrence group,and the remained ones were divided into a non-recurrence group.The recurrence group went through HR-VWI scanning within two weeks of recurrence and statin treatment,and the non-recurrence group was examined with HR-VWI half a year after receiving statin treatment.All the patients had their clinical indexes compared before and after statin treatment,the baseline data of the two groups underwent univariate analysis,and Logistic regression analysis was performed for the high-risk factors related to recurrence.SPSS 22.0 software was used for statistical analysis.Results After six months of statin treatment,all the patients were improved in TC,TG,luminal stenosis rate,high T1WI signal,plaque burden,plaque enhancement rate and NIHSS score,with the differences being significant(all P＜0.05).Univariate analysis showed the recurrence group had higher plaque enhancement rates(P=0.012)and higher plaque burden(P=0.047)when compared with the non-recurrence group,with the differences being significant;the two groups were not statistically different in luminal stenosis rate,high T1WI signal,plaque thickness and remodeling index(all P＞0.05).Multivariate logistic regression analysis indicated the plaque enhancement rate was independently correlated with stroke recurrence within 6 months(P=0.027).Conclusion HR-VWI can effectively assess MCA plaque characteristics in recurrent stroke patients,and high plaque enhancement rate faciliates the evaluation of stroke recurrence.[Chinese Medical Equipment Journal,2025,46(2):63-67]关键词
脑卒中/高分辨磁共振血管壁成像/大脑中动脉/粥样硬化/斑块特征/脑卒中复发Key words
stroke/high resolution vessel wall imaging/middle cerebral artery/atherosclerosis/plaque characteristic/stroke recurrence分类
基础医学引用本文复制引用
曾星星,王莉蓉,高志国,鲁金飞,蒋小莉,李小依..基于高分辨磁共振血管壁成像的症状性大脑中动脉粥样硬化斑块特征与脑卒中复发风险关系研究[J].医疗卫生装备,2025,46(2):63-67,5.基金项目
荆门市科技局引导项目(2023YDKY038) （2023YDKY038）
