眼科新进展2025，Vol.45Issue(3)：247-252,6.DOI:10.13389/j.cnki.rao.2025.0044
氧化应激在眼部疾病中的作用机制及治疗策略研究
Study on the mechanism of oxidative stress in ocular diseases and therapeutic strategies
摘要
Abstract
An imbalance between oxidative and antioxidant defense mechanisms in the body triggers oxidative stress,which causes a series of damages to the body,tissues and cells.The eye is particularly susceptible to oxidative stress due to its prolonged exposure to light and its anatomical characteristics of high metabolism and oxygen consumption.In addi-tion,inflammation,aging,genetic and environmental factors can promote the production of reactive oxygen species and weaken antioxidant defense mechanisms,which are all risk factors for oxidative stress that can lead to a variety of ocular diseases.The aim of this paper is to review the mechanisms of oxidative stress in ocular diseases such as ocular surface diseases,glaucoma,cataract,and retinopathy.At the same time,the potential therapeutic approaches to these diseases by regulating oxidative stress are discussed,so as to provide new ideas and directions for the diagnosis and treatment of ocular diseases.关键词
氧化应激/眼部疾病/发病机制/活性氧/抗氧化剂Key words
oxidative stress/eye disease/pathogenesis/reactive oxygen species/antioxidants分类
医药卫生引用本文复制引用
王灿宇,杨锐煜,邵毅,廖萱..氧化应激在眼部疾病中的作用机制及治疗策略研究[J].眼科新进展,2025,45(3):247-252,6.基金项目
四川省科技厅自然科学基金项目(编号:2023NSFSC0595) （编号:2023NSFSC0595）
川北医学院附属医院科研发展计划重点项目(编号:2023ZD010) （编号:2023ZD010）
