中国临床医学影像杂志2025，Vol.36Issue(2)：127-130,4.DOI:10.12117/jccmi.2025.02.012
二维横切面上胼胝体长度与枕额径比值对胎儿胼胝体长度变短的诊断价值研究
Research on the diagnostic value of corpus callosum length to occipitofrontal diameter proportion on two-dimensional axial plane for fetal short corpus callosum
摘要
Abstract
Objective:To establish the normal reference range of the ratio of corpus callosum length to occipitofrontal di-ameter on two-dimensional axial plane and explore its diagnostic value for short corpus callosum.Methods:A total of 360 cases of normal fetuses(normal group)and 76 cases of fetuses with suspected short corpus callosum confirmed by prenatal/postnatal MRI(abnormal group)were selected from January 2020 to December 2023,who underwent prenatal ultrasound exami-nation using the two-dimensional transverse section method in our hospital.Additionally,48 cases of fetuses with fetal growth restriction(FGR group)were clinically diagnosed.The maximum anterior-posterior diameter of the corpus callosum on the trans-verse section was measured for all fetuses,and the ratio of corpus callosum length to occipitofrontal diameter was calculated.The normal reference values for the ratio of corpus callosum length to occipitofrontal diameter in normal fetuses were estab-lished,and composite scatter plots of the ratio of corpus callosum length to occipitofrontal diameter were created for the ab-normal group,FGR group,and normal group.Results:The maternal ages of the 360 cases in the normal group,76 cases in the abnormal group,and 48 cases in the FGR group were 30.6±4.6 years old,31.5±7.9 years old,and 30.7±4.5 years old,respectively.There was no statistically significant difference in maternal age among the three groups when compared pairwise(P=0.152 between normal group and abnormal group,P=0.457 between normal group and FGR group,P=0.083 between abnor-mal and FGR group).There were statistically significant differences in the ratio of corpus callosum length to occipitofrontal di-ameter in both the abnormal group and FGR group(P<0.05)when compared with the normal group.The composite scatter plots of the ratio of corpus callosum length to occipitofrontal diameter for the abnormal group,FGR group,and normal group showed that the ratio in the abnormal cases was significantly lower than the 5th percentile line of the normal cases,while the difference between the FGR cases and abnormal cases was not significant.Conclusion:The ratio of corpus callosum length to occipitofrontal diameter on two-dimensional transverse section has reference value for assessing corpus callosum size,and the ratio remains relatively constant throughout gestational weeks.Moreover,this ratio is also normal in FGR fetuses,which can avoid misdiagnosis of corpus callosum dysplasia due to the actual length of the corpus callosum being lower in FGR fetuses than in normal fetuses.关键词
胎儿发育/胼胝体/超声检查,多普勒,彩色Key words
Fetal Development/Corpus Callosum/Ultrasonography,Doppler,Color分类
临床医学引用本文复制引用
文桂琼,曾晴,李琴,柳元铭..二维横切面上胼胝体长度与枕额径比值对胎儿胼胝体长度变短的诊断价值研究[J].中国临床医学影像杂志,2025,36(2):127-130,4.基金项目
广西壮族自治区卫生健康委自筹经费科研课题(Z-C20230810). （Z-C20230810）
