中国临床医学影像杂志2025，Vol.36Issue(2)：131-136,6.DOI:10.12117/jccmi.2025.02.013
DTI联合椎体脂肪及椎旁肌脂肪半定量评分在腰椎间盘退变中的应用研究
DTI combined with semi-quantitative scoring of vertebral body fat and paravertebral muscle fat for evaluation of lumbar intervertebral disc degeneration
摘要
Abstract
Objective:To analyze the application of fractional anisotropy(FA)and apparent diffusion coefficient(ADC)de-rived from diffusion tensor imaging(DTI)in assessing lumbar intervertebral disc degeneration,evaluating their value in quantify-ing the degree of degeneration.Additionally,to investigate the association between disc degeneration and adjacent vertebral body and paraspinal muscle fat infiltration,elucidating whether disc degeneration represents a synergistic musculoskeletal dis-order.Methods:A total of 60 patients meeting inclusion criteria between September 2022 and October 2023 were enrolled,undergoing both lumbar MRI and DTI scans.Demographic data(age,sex,anatomic level)were collected,and two radiologists independently evaluated imaging findings.Intraclass correlation coefficients(ICCs)were used to assess inter-rater agreement.Dif-ferences in FA and ADC values,vertebral body and paraspinal muscle fat infiltration scores across different PM grades were compared,and correlations between PM grade,age,anatomic level,DTI parameters,and fat infiltration scores were analyzed.Results:ICCs for measurements by both radiologists were>0.75,indicating good consistency,except for the right erector spinae muscle.No statistically significant differences were observed in bilateral erector spinae fat infiltration scores among dif-ferent PM grades(P>0.05),while FA,ADC,fat infiltration scores of upper and lower vertebrae,and bilateral multifidus and erector spinae muscles showed significant differences(P<0.05).FA demonstrated a strong correlation with PM grade(rFA=0.748),while ADC,anatomic level,age,and upper vertebral fat infiltration were moderately correlated(rADC=-0.539,ranatomic level=0.571,rage=0.471,rupper vertebral=0.371).Lower vertebral fat infiltration and bilateral multifidus and erector spinae muscle fat infiltration exhib-ited weak correlations(rlower vertebral=0.250,rright multifidus=0.185,rleft multifidus=0.198,rright erector spinae=0.102,rleft erector spinae=0.126).Bilateral erector spinae muscles showed no correlation with PM grade.Conclusion:FA and ADC values are useful for quantitatively assessing the degree of lumbar intervertebral disc degeneration,and disc degeneration indeed manifests as a synergistic,holistic muscu-loskeletal disorder.关键词
椎间盘退行性变/磁共振成像Key words
Intervertebral Disc Degeneration/Magnetic Resonance Imaging分类
医药卫生引用本文复制引用
宋绍文,李晓静,王凤,郭会利,刘玉珂,张斌青..DTI联合椎体脂肪及椎旁肌脂肪半定量评分在腰椎间盘退变中的应用研究[J].中国临床医学影像杂志,2025,36(2):131-136,6.基金项目
河南省医学科技攻关计划基金资助项目(LHGJ20230484). （LHGJ20230484）
