中国临床医学2025，Vol.32Issue(1)：9-14,6.DOI:10.12025/j.issn.1008-6358.2025.20241508
钇-90微球选择性内放射治疗在肝细胞癌降期转化中的研究进展
Research progress of Yttrium-90 microsphere selective internal radiation therapy in downstaging and conversion of hepatocellular carcinoma
摘要
Abstract
The incidence and mortality of hepatocellular carcinoma(HCC)in China are among the highest in the world,imposing a heavy social burden.Liver resection and liver transplantation are the primary radical treatments for HCC,although most patients are no longer able to meet the surgical requirements at initial diagnosis.Yttrium-90 microsphere selective internal radiation therapy(90Y-SIRT)has the advantages of shrinking tumors,enlarging residual liver,regressing portal vein tumor thrombus and improving the quality of life,which can be used for conversion,downstaging and bridging therapy for HCC before surgical treatment,enabling patients regain the chance of radical treatment and reducing the postoperative recurrence rate.This review focuses on the clinical application and progress of 90Y-SIRT in this field.关键词
肝细胞癌/钇-90/选择性内放射治疗/降期治疗/转化治疗/桥接治疗Key words
hepatocellular carcinoma/Yttrium-90/selective internal radiation therapy/downstaging therapy/conversion therapy/bridging therapy分类
临床医学引用本文复制引用
梁礼聪,梁钰婵,黄文薮,郭永建,黄敬君,林立腾,蔡明岳,朱康顺..钇-90微球选择性内放射治疗在肝细胞癌降期转化中的研究进展[J].中国临床医学,2025,32(1):9-14,6.基金项目
广州地区临床高新和重大技术项目.Supported by Project of Clinical High-Tech and Major Technology in Guangzhou. （）
