中国输血杂志2025，Vol.38Issue(2)：227-232,243,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.02.011
红细胞类血液成分质量监测数据的评估与探讨
Assessment and discussion of quality monitoring data for red blood cell preparations
摘要
Abstract
Objective To assess the data characteristics of quality monitoring indicators for red blood cell(RBC)prep-arations,so as to provide reference for continuous improvement of blood quality.Methods The quality inspection data of 6 types of RBC preparations from Chongqing blood center from 2019 to 2023 were summarized.For the same indicators,the numerical range of quality indicators was monitored by comparing different types of preparations with the national standard GB18469.The loss and/or damage to RBCs caused by different preparation process were compared,and the impact of dif-ferent preparation processes on the quality of RBCs was discussed.Results The appearance and sterility test compliance rates of the six types of RBC preparations were both 100%,while the compliance rates of other items were all≥75%.The compliance rate of hematocrit for suspended RBCs was the lowest at 75%,with a median of 0.52,which was close to the lower limit of GB18469,while the medians of hematocrit for the other types were all at the midline level of GB18469.The Hb content for different types of RBCs was significantly higher than the corresponding requirements of GB18469(P<0.05).The hemolysis rate at the end of storage for different types of RBCs was significantly lower than the requirements of GB18469(P<0.05).The 1 U leukoreduction process resulted in a hemoglobin content loss of about 5%and had a significant impact on the hemolysis rate at the end of storage(P<0.05).The washing process resulted in a hemoglobin content loss of<3%and had no significant impact on the hemolysis rate at the end of storage(P>0.05).The concentration process resulted in a hemoglobin content loss of<3%and had a significant impact on the hemolysis rate at the end of storage(P<0.05).Con-clusion The impact of different processes on RBC preparations is within a controllable range and meets the requirements of GB18469.The quality monitoring data can provide a reference for clinical blood selection,effectiveness evaluation and revi-sion of related standards.关键词
红细胞/血液成分/质量差异/质量控制/GB18469Key words
red blood cells(RBCs)/blood components/quality variability/quality control/GB18469分类
临床医学引用本文复制引用
卿芸,代华友,杨俊鸿,许茜,吴思其,田耘博,黄霞..红细胞类血液成分质量监测数据的评估与探讨[J].中国输血杂志,2025,38(2):227-232,243,7.基金项目
重庆市卫生健康委医学科研项目(2024WSJK062) （2024WSJK062）
