中国输血杂志2025，Vol.38Issue(2)：233-237,5.DOI:10.13303/j.cjbt.issn.1004-549x.2025.02.012
单采血小板细菌污染的单中心回顾性分析
Bacterial contamination of platelets apheresis:a single-center retrospective analysis
罗圆圆 1马春娅 1付丽辉 1王泽珊 1于洋1
作者信息
- 1. 中国人民解放军总医院第一医学中心 输血医学科,北京 100853
- 折叠
摘要
Abstract
Objective To evaluate the risk of bacterial contamination of platelets apheresis and improve the clinical di-agnosis rate of transfusion-transmitted bacterial infections.Methods A retrospective analysis was conducted on 11 cases involving bacterial contamination detected in apheresis platelets during quality inspections at our center from 2021 to 2023,as well as cases of transfusion-transmitted bacterial infection(TTBI)caused by platelet transfusion.The return of positive platelet bacteria test results and clinical transfusion adverse reactions were statistically analyzed.Results There were 9 do-nors with bacteria-contaminated platelets,of which 3 were reported as clinical transfusion reaction,4 were detected by qual-ity sampling,and 2 were identified by appearance detection before transfusion.The bacterial contamination rate of platelets was about 0.08%(9/10 762).The contaminated platelets were involved in 11 cases of TTBI,with an incidence of TTBI of approximately 0.05%(11/21 916).Only 3 cases of transfusion reactions were clinically reported,while the rest were case tracking with positive results of platelet bacterial test from quality sampling.The clinical return rate of TTBI was 27.27%(3/11),with an average reporting time of 8.12 hours after the occurrence of transfusion reactions.The majority of the con-taminated platelets were detected at the end stage of storage,with 55.56%(5/9)of platelets collected on the 4th day after collection.Partial contaminated platelets were identified through quality sampling,with a positive rate of 2.78%(4/144).Conclusion The platelet bacterial contamination rate is high,but with low clinical return rate.It is recommended to con-duct routine platelet bacterial monitoring and improve clinical diagnostic level.关键词
输血传播细菌感染/单采血小板/细菌污染/诊断率Key words
transfusion-transmitted bacterial infection/platelets apheresis/bacterial contamination/diagnostic rate分类
基础医学引用本文复制引用
罗圆圆,马春娅,付丽辉,王泽珊,于洋..单采血小板细菌污染的单中心回顾性分析[J].中国输血杂志,2025,38(2):233-237,5.
