中国输血杂志2025，Vol.38Issue(2)：238-243,6.DOI:10.13303/j.cjbt.issn.1004-549x.2025.02.013
从供者流失对血小板库建库策略进行分析评估
Analysis and evaluation of platelet bank establishment strategy from the perspective of donor loss
摘要
Abstract
Objective To analyze the loss rate of platelet donors and evaluate the strategies for establishing a platelet donor bank.Methods A total of 1 443 donors who joined the HLA and HPA gene donor bank for platelets in Henan Prov-ince from 2018 to 2020 were included in this study.Data on the total number of apheresis platelet donations,annual dona-tion frequency,age at enrollment,donation habits(including the number of platelets donated per session and whether they had previously donated whole blood),and enrollment location were collected from the platelet donor information manage-ment system.Donor loss was determined based on the date of their last donation.The loss rates of different groups under va-rious conditions were compared to assess the enrollment strategies.Results By the time the platelet bank was officially op-erational in 2022,421 donors had been lost,resulting in an loss rate of 29%(421/1 443).By the end of 2023,the overall cumulative loss rate reached 52%(746/1 443).The loss rate was lower than the overall level in groups meeting any of the following conditions:total apheresis platelet donations exceeding 50,annual donation frequency of 10 or more,age at enroll-ment of 40 years or older,donation of more than a single therapeutic dose per session,or a history of whole blood donation two or more times.Additionally,loss rates varied across different enrollment locations,with higher enrollment numbers gen-erally associated with higher loss rates.Conclusion Through a comprehensive analysis of donor loss,our center has adjus-ted its strategies for establishing the donor pool.These findings also provide valuable insights for other blood collection and supply institutions in building platelet donor banks.关键词
供者流失/血小板供者库/血小板输注无效/人类白细胞抗原/人类血小板抗原Key words
donor loss/platelet donor bank/platelet transfusion refractoriness/human leukocyte antigen/human platelet antigen分类
临床医学引用本文复制引用
刘铮,孙亚敏,彭鑫,康轶青,王子清,朱锦彤,杜娟,李建斌..从供者流失对血小板库建库策略进行分析评估[J].中国输血杂志,2025,38(2):238-243,6.基金项目
河南省医学科技攻关项目(201503198) （201503198）
河南省医学科技攻关计划联合共建项目(LHGJ20230609) （LHGJ20230609）
