中国实用外科杂志2025，Vol.45Issue(1)：5-10,6.DOI:10.19538/j.cjps.issn1005-2208.2025.01.02
异种移植:从基础到临床的瓶颈与对策
Xenotransplantation:bottlenecks and countermeasures in clinical transformation
摘要
Abstract
With the increase in life expectancy of human beings,the number of patients with chronic diseases and end-stage organ failure is growing.Organ transplantation,which is considered as an effective treatment,is limited by the severe shortage of donor organs.In this context,xenotransplantation emerges as a promising alternative therapy,showing great potential to meet the pressing demand of donor organs,tissues and cells.Owing to the development of the relevant theories and technologies such as gene editing,immunosuppression and organ preservation,the feasibility of clinical xenotransplantation is increasing.Nevertheless,the clinical application of xenotransplantation is still in the preliminary stage of exploration.关键词
异种移植/器官移植/基因编辑技术/凝血功能障碍/感染Key words
xenotransplantation/organ transplantation/gene editing technology/coagulation disorders/infection分类
临床医学引用本文复制引用
窦科峰,林智斌,马先一..异种移植:从基础到临床的瓶颈与对策[J].中国实用外科杂志,2025,45(1):5-10,6.基金项目
国家自然科学基金项目(No.82371793,No.82070671,No.82400667) National Natural Science Foundation of China(No.82371793,No.82070671,No.82400667) （No.82371793,No.82070671,No.82400667）
