中国实用外科杂志2025，Vol.45Issue(1)：48-51,58,5.DOI:10.19538/j.cjps.issn1005-2208.2025.01.07
美国癌症联合委员会第9版胃肠胰神经内分泌肿瘤分期系统解读
Interpretation of the American Joint Committee on Cancer(AJCC)9th Edition Staging System for patients with gastroenteropancreatic neuroendocrine tumors
摘要
Abstract
Gastroenteropancreatic neuroendocrine tumors(GEP-NETs)exhibit significant heterogeneity and complex prognostic factors,presenting a longstanding challenge in standardizing treatment to improve long-term patient survival.The American Joint Committee on Cancer(AJCC)implemented the 9th edition of the staging system for GEP-NETs in January 2024.Compared to the previous edition,the new system includes several updates:further staging for Nx tumors of the stomach,duodenum/ampulla,appendix,and colon/rectum;emphasize of the importance of endoscopic diagnosis and treatment;emphasis on the diagnosis and treatment of PPI-related gastric neuroendocrine tumors;and updates on certain diagnostic markers and prognostic factors.Overall,the staging system is becoming more precise and comprehensive.The AJCC staging system holds authoritative influence worldwide,and it is anticipated that future evidence-based medical research will further standardize the treatments of GEP-NETs.关键词
胃肠胰神经内分泌肿瘤/AJCC分期/肿瘤异质性/内镜治疗/肿瘤标记物Key words
gastroenteropancreatic neuroendocrine tumors/AJCC staging/tumor heterogeneity/endoscopic treatment/tumor markers分类
临床医学引用本文复制引用
吴嘉文,李启元,孙备..美国癌症联合委员会第9版胃肠胰神经内分泌肿瘤分期系统解读[J].中国实用外科杂志,2025,45(1):48-51,58,5.基金项目
国家自然科学基金项目(No.82270665,No.82470672) （No.82270665,No.82470672）
黑龙江省科学技术厅重点研发计划(创新基地)基金资助项目(No.JD2023SJ42) National Natural Science Foundation of China(No.82270665,No.82170672) （创新基地）
Key Research and Development Program(Innovation Base)Fund of Heilongjiang Provincinal Department of Science and Technology(No.JD2023SJ42) （Innovation Base）
