中国输血杂志2025，Vol.38Issue(2)：194-200,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.02.006
骨折端富血小板血浆注射联合微骨折术治疗骨折延迟愈合的临床应用观察
Injection of platelet-rich plasma at the fracture site combined with microfracture surgery for the treatment of de-layed fracture healing
摘要
Abstract
Objective To report a new technique that combines microfracture surgery under local anesthesia with injec-tion of platelet-rich plasma(PRP)at the fracture site,so as to improve fracture healing rates.Methods Data from patients who visited our hospital from March 2020 to June 2023 and underwent the treatment for delayed union of limb fractures were retrospectively analyzed.Under local infiltrative anesthesia,with the assistance of a C-arm X-ray machine or ultrasound,percutaneous loosening was done at the fracture site and the medullary cavity,followed by cortical drilling around the frac-ture.The previously prepared PRP was then injected locally at the fracture site.Patients were followed up and their postop-erative recovery was recorded.Results All patients were followed up,and the fracture healing rate was 94.12%(16/17),with an average healing duration of(5.88±2.50)months.None of the patients experienced any neural or vascular injuries,nor adverse events such as wound infections or osteomyelitis.Before the operation and at the last follow-up,the patients'pain visual analogue scores were(5.12±1.11)vs(0.71±1.21)respectively.The postoperative VAS scores showed a sig-nificant decrease compared to preoperative values(P<0.05).The excellent and good rate for limb function on the affected side was 88.24%(14/17)at the last follow-up,which was a significant increase from 0.00%before surgery(P<0.05).Conclusion The injection of PRP at the fracture site combined with microfracture surgery at the fracture site is minimally invasive,simple to perform,and well-accepted by patients.It has demonstrated some clinical efficacy in treating delayed fracture healing.关键词
富血小板血浆/微骨折手术/骨折延迟愈合Key words
platelet-rich plasma(PRP)/microfracture surgery/delayed fracture union分类
医药卫生引用本文复制引用
涂俊波,黄晓武,李兴旺,李晓清..骨折端富血小板血浆注射联合微骨折术治疗骨折延迟愈合的临床应用观察[J].中国输血杂志,2025,38(2):194-200,7.基金项目
江西省卫生健康委科技计划项目(SKJP220228540) （SKJP220228540）
