中国医学创新2025，Vol.22Issue(6)：21-24,4.DOI:10.3969/j.issn.1674-4985.2025.06.005
腹横肌平面阻滞与切口局部浸润麻醉对单孔腹腔镜胆囊切除术患者切口疼痛及炎症应激反应的影响
Effects of Transversus Abdominis Plane Block and Incision Local Infiltration Anesthesia on Incision Pain and Inflammatory Stress Response in Patients Undergoing Single Incision Laparoscopic Cholecystectomy
摘要
Abstract
Objective:To investigate the effects of transversus abdominis plane block(TAPB)and incision local infiltration anesthesia(LIA)on incision pain and inflammatory stress response in patients undergoing single incision laparoscopic cholecystectomy(SILC).Method:A total of 94 patients received SILC admitted to Department of General Surgery,Zhongshan Dongfeng People's Hospital from June 2022 to June 2024 were selected and randomly divided into two groups,with 47 cases in each group.Both groups received SILC,the observation group received TAPB,and the control group received incision LIA.The numerical rating scale(NRS),the levels of inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and interleukin-8(IL-8)]and hospital stay were compared between the two groups.Result:NRS scores 30 min,2 h and 6 h after operation in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).1 weeks after operation,the levels of TNF-α,IL-6 and IL-8 in observation group were lower than those in control group,the differences were statistically significant(P<0.05).The hospital stay in the observation group was shorter than that in the control group(P<0.05).Conclusion:The application of TAPB in patients undergoing SILC can not only significantly reduce the degree of pain,but also alleviate inflammatory stress response and promote rapid recovery of patients.关键词
腹横肌平面阻滞/切口局部浸润麻醉/单孔腹腔镜胆囊切除术/疼痛/炎症应激反应Key words
Transversus abdominis plane block/Incision local infiltration anesthesia/Single incision laparoscopic cholecystectomy/Pain/Inflammatory stress response引用本文复制引用
梅锋,干雯,徐伟宏,余汉辉,龙响良..腹横肌平面阻滞与切口局部浸润麻醉对单孔腹腔镜胆囊切除术患者切口疼痛及炎症应激反应的影响[J].中国医学创新,2025,22(6):21-24,4.基金项目
中山市第一批社会公益与基础研究项目(2022B1155) （2022B1155）
