中国中医急症2025，Vol.34Issue(2)：314-317,4.DOI:10.3969/j.issn.1004-745X.2025.02.033
退高黄汤治疗戊型肝炎(瘀热互结证)的临床观察
Clinical Study of Tuigaohuang Decoction in the Treatment of Hepatitis E(Syndrome of Intermingled Phlegm and Blood Stasis)
摘要
Abstract
Objective:To observe the clinical efficacy of Tuigaohuang Decoction in treating patients with Hepa-titis E(syndrome of intermin-gled phlegm and blood stasis)and its impact on lymphocyte subsets.Methods:72 patients diagnosed with Hepatitis E were selected and randomly divided into a treatment group and a control group,each with 36 cases.The treatment group received Tuigaohuang Decoction in addition to comprehensive in-ternal medicine treatment,while the control group received placebo alongside comprehensive treatment.Relevant indicators were compared between the two groups before and after treatment.Results:Compared with the control group,the treatment group showed more significant decreases in total bilirubin(TBil),increases in prealbumin(PA),CD4,and CD4/CD8 ratios;greater reductions in the main portal vein diameter,and more significant increas-es in blood flow volume and velocity;more significant decreases in hyaluronic acid(HA),type Ⅲ collagen(PⅢP),type Ⅳ collagen(PⅣP),laminin(LN),and liver stiffness measurement(LSM);and better overall efficacy rates and improvements in total symptom scores(all P<0.05).Safety indicators remained normal during the treatment period for both groups.Conclusion:Tuigaohuang Decoction effectively reduces total bilirubin levels in patients with Hep-atitis E,regulates cellular immune function,shows good effects in inhibiting liver inflammation development,im-proves hepatic microcirculation,and blocks fibrosis progression,which has broad application value.关键词
戊型肝炎/退高黄汤/中医药/瘀热互结证Key words
Hepatitis E/Tuigaohuang Decoction/Traditional Chinese medicine/Clinical efficacy分类
医药卫生引用本文复制引用
姚超,俞冲,朱琦琦..退高黄汤治疗戊型肝炎(瘀热互结证)的临床观察[J].中国中医急症,2025,34(2):314-317,4.基金项目
江苏省中医药管理局科技发展计划项目(MS2023115) （MS2023115）
南通市卫生健康委科研课题(QNZ2022037) （QNZ2022037）
