中国医学创新2025，Vol.22Issue(6)：63-67,5.DOI:10.3969/j.issn.1674-4985.2025.06.015
Neuroform EZ支架在症状性大脑中动脉M1段狭窄病变介入治疗中的效果及对神经损伤的影响
Application Effect of Neuroform EZ Stent in Interventional Treatment of Patients with Symptomatic Stenosis of the M1 Segment of the Middle Cerebral Artery and Influence on Neurological Injury
摘要
Abstract
Objective:To investigate the application effect of Neuroform EZ stent in interventional treatment of patients with symptomatic M1 segment stenosis of middle cerebral artery and influence on neurological injury.Method:A total of 80 patients with symptomatic M1 segment stenosis of middle cerebral artery hospitalized in Qinzhou Second People's Hospital from January 2021 to March 2023 were divided into control group 40 cases and observation group 40 cases by the random number table.The control group was treated with medicine treatment,the observation group was treated with Neuroform EZ stent on the treatment of control group.The patients were followed up after 6 and 12 months of treatment.The total effective rates,adverse vascular events rates,cerebral blood flow perfusion situation[cerebral blood volume(CBV)and cerebral blood flow(CBF)],national institute of health stroke scale(NIHSS)score,modified Rankin scale(MRS)score and neurological injury indexes[serum neuron-specific enolase(NSE)and S100 calcium-binding protein B(S100B)]before and after the treatment of two groups were compared.Result:The total postoperative effective rate of observation group was significantly higher than that of control group,the adverse vascular events rate was significantly lower than that of control group(P<0.05),the cerebral blood flow perfusion situation,NIHSS score,MRS score and neurological injury indexes of two groups before the treatment were compared,the differences were not statistically significant(P>0.05),the CBV and CBF of observation group after 6 and 12 months of the treatment were significantly higher than those of control group,the NIHSS scores,MRS scores and neurological injury indexes after 1 and 2 weeks of the treatment were all significantly lower than those of control group(P<0.05).Conclusion:The effect of Neuroform EZ stent in interventional treatment of patients with symptomatic stenosis of the M1 segment of the middle cerebral artery is better,and it can effectively control the neurological injury of patients,so its application value in patients with symptomatic stenosis of the M1 segment of the middle cerebral artery is high.关键词
Neuroform EZ支架/症状性大脑中动脉M1段狭窄/神经损伤Key words
Neuroform EZ stent/Symptomatic stenosis of M1 segment of middle cerebral artery/Neurological injury引用本文复制引用
吴亮,彭富,周传凯,牙政锋,廖振南..Neuroform EZ支架在症状性大脑中动脉M1段狭窄病变介入治疗中的效果及对神经损伤的影响[J].中国医学创新,2025,22(6):63-67,5.基金项目
广西壮族自治区卫生健康委员会自筹经费科研课题(Z20211407) （Z20211407）
