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Lp(a)、MMP-9及NLR与动脉粥样硬化关系的研究进展

徐轶明 艾荣杰 赵明 杨焱

中国医药科学2025,Vol.15Issue(2):24-27,4.
中国医药科学2025,Vol.15Issue(2):24-27,4.DOI:10.20116/j.issn2095-0616.2025.02.06

Lp(a)、MMP-9及NLR与动脉粥样硬化关系的研究进展

Research progress on the correlation between Lp(a),MMP-9 and NLR and atherosclerosis

徐轶明 1艾荣杰 1赵明 2杨焱3

作者信息

  • 1. 内蒙古民族大学临床医学院,内蒙古 通辽 028000
  • 2. 内蒙古民族大学附属医院心血管内科,内蒙古 通辽 028000
  • 3. 内蒙古民族大学附属医院全科医疗科,内蒙古 通辽 028000
  • 折叠

摘要

Abstract

Coronary atherosclerosis heart disease is threatening the health of China residents.Its pathogenesis is the destruction of endothelial cells in coronary artery,which impacts the protective effect of intima,makes the fat on the vascular wall accumulate,causes the lumen of coronary artery to narrow or even block,and finally causes myocardial cells to die of ischemia and hypoxia.This process is called atherosclerosis.The development of atherosclerosis and plaque rupture are greatly impacted by inflammation,so it is of great clinical value to investigate more inflammatory biomarkers that may participate in the formation of atherosclerosis.Research have shown that lipoprotein(a),matrix metalloproteinase-9 and neutrophil to lymphocyte ratio are all involved in the inflammatory process,and they are related to the occurrence and development of atherosclerosis.This article reviews their relationship with atherosclerosis.

关键词

脂蛋白(a)/基质金属蛋白酶9/中性粒细胞与淋巴细胞比值/动脉粥样硬化

Key words

Lipoprotein(a)/Matrix metalloproteinase-9/Neutrophil to lymphocyte ratio/Atherosclerosis

分类

临床医学

引用本文复制引用

徐轶明,艾荣杰,赵明,杨焱..Lp(a)、MMP-9及NLR与动脉粥样硬化关系的研究进展[J].中国医药科学,2025,15(2):24-27,4.

基金项目

内蒙古自治区自然科学基金项目(2022MS08082). (2022MS08082)

中国医药科学

2095-0616

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