中国医学创新2025,Vol.22Issue(6):108-111,4.DOI:10.3969/j.issn.1674-4985.2025.06.025
结直肠息肉患者高同型半胱氨酸血症与肾功能的相关性分析
Correlation Analysis between Hyperhomocysteinemia and Renal Function in Patients with Colorectal Polyps
摘要
Abstract
Objective:To explore the correlation between homocysteine(Hcy)level and renal function in patients with colorectal polyps.Method:A total of 121 cases with colorectal polyps who underwent colonoscopy in Lingshan County People's Hospital from July 2021 to July 2023 were selected as the study objects.According to serum Hcy level,the patients were divided into control group(Hcy<15 μmol/L)with 77 cases,and hyperhomocysteinemia(HHcy)group(Hcy≥15 μmol/L)with 44 cases.The clinical features and renal function of the two groups were compared,and the correlation between serum Hcy level and renal function in patients with colorectal polyps was analyzed.Result:Compared with control group,serum creatinine,urea and uric acid levels in HHcy group were significantly higher,with statistical significance(P<0.05).According to Pearson correlation coefficient analysis,serum creatinine and uric acid levels were positively correlated with Hcy levels in two groups(r=0.407,0.315,P<0.05).Conclusion:Serum creatinine and uric acid levels are associated with serum Hcy levels,and for patients with HHcy levels of colorectal polyps,it is necessary to monitor renal function.关键词
结直肠息肉/高同型半胱氨酸血症/肾功能/相关性分析Key words
Colorectal polyps/Hyperhomocysteinemia/Kidney function/Correlation analysis引用本文复制引用
罗艺珍,仇继峰,黄林妮..结直肠息肉患者高同型半胱氨酸血症与肾功能的相关性分析[J].中国医学创新,2025,22(6):108-111,4.基金项目
钦州市科学研究与技术开发计划项目(20213722) (20213722)