中国医药科学2025，Vol.15Issue(2)：49-52,4.DOI:10.20116/j.issn2095-0616.2025.02.12
基于血流动力学、镇痛效果分析右美托咪定用于老年患者髋部骨折术的效果
Analysis on the effect of dexmedetomidine on hip fracture surgery in elderly patients based on hemodynamics and analgesic effect
摘要
Abstract
Objective To analyze the effect of dexmedetomidine on hip fracture surgery in elderly patients based on hemodynamics and analgesic effect.Methods A total of 84 elderly patients with hip fracture admitted to and treated in the Jilin Integrated Traditional Chinese and Western Medicine Hospital from January 2021 to January 2023 were selected and divided into the control group(n=42)and the observation group(n=42)according to the random number table method.Patients in both groups underwent hip fracture surgery under anesthesia induction.On this basis,the control group was combined with intravenous infusion of 0.9%normal saline,while the observation group was combined with intravenous infusion of the same dose of dexmedetomidine.The perioperative indices(anesthesia time,intraoperative infusion volume and intraoperative hemorrhage volume),postoperative hemodynamics(mean arterial pressure,diastolic arterial pressure,systolic arterial pressure and heart rate),visual analogue scale(VAS)pain score changes and postoperative complications(hypotension,cough,vomiting and bradycardia)were compared between the two groups.Results There were no statistically significant differences in anesthesia time,intraoperative infusion volume and intraoperative hemorrhage volume between the two groups(P>0.05).The hemodynamics indices and pain in the two groups all changed with time,and the hemodynamics indices and pain in the observation group were smaller than those in the control group,with statistically significant differences(P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group,with statistically significant differences(P<0.05).Conclusion The use of dexmedetomidine in elderly patients with hip fracture during surgery can significantly reduce postoperative pain,ensure hemodynamic stability,and has high safety.Therefore,dexmedetomidine deserves to be widely applied in the hip joint fracture surgery of the elderly.关键词
血流动力学/镇痛效果/髋部骨折术/右美托咪定Key words
Hemodynamics/Analgesic effect/Hip fracture surgery/Dexmedetomidine分类
医药卫生引用本文复制引用
陈鑫,霍大勇,王雪飞,张建勋..基于血流动力学、镇痛效果分析右美托咪定用于老年患者髋部骨折术的效果[J].中国医药科学,2025,15(2):49-52,4.基金项目
吉林省中医药科技项目(2024302). （2024302）
