中国医药科学2025，Vol.15Issue(2)：53-56,4.DOI:10.20116/j.issn2095-0616.2025.02.13
曲马多联合布托啡诺对重复剖宫产术后子宫痉挛性疼痛的镇痛作用
Analgesic effect of tramadol combined with butorphanol on uterine spasmodic pain after repeated cesarean section
摘要
Abstract
Objective Exploring the analgesic effect,efficacy,and safety of tramadol combined with butorphanol on uterine spasmodic pain in women undergoing repeated cesarean section.Methods A total of 118 multiparous women who underwent two or more cesarean sections at Huizhou First Maternal and Child Health Care Hospital from September 2022 to April 2023 were selected as the study subjects.According to the computer random number table method,the parturients were divided into the sufentanil group(58 cases)and the tramadol combined with butorphanol group(60 cases).The resting and motor numerical pain rating scale(NRS)scores of uterine spasticity pain and abdominal incision pain were recorded for both groups of parturients at 6,12,24,and 48 h after cesarean section.The Pittsburgh sleep quality index(PSQI)was used to evaluate the sleep quality of two groups of parturients on the day of surgery and the first day after surgery.Record the occurrence of adverse events such as itching,nausea,vomiting,and respiratory depression in two groups of postpartum women after surgery.Record the number of postoperative pain relief cases in two groups.Results The resting and motor NRS scores of transwomen with uterine spasmodic pain in the tramadol combined with butorphanol group were lower than those of the sufentanil group at the 6,12,and 24 h time points,and the difference was statistically significant(P<0.05).The comparison of resting and motor NRS scores of transwomen with abdominal incisional pain in the two groups at any time point were not statistically significant(P>0.05).The PSQI scores of transwomen on the day of surgery and postoperative day 1 in the tramadol combined with butorphanol group were lower than those of the sufentanil group,and the difference was statistically significant(P<0.05).The total incidence of adverse events and analgesic remediation rate of the two groups were compared,and the difference was not statistically significant(P>0.05).Conclusion The combination of tramadol and butorphanol has shown promising application prospects in postoperative pain management after cesarean section,especially in the analgesic effect of early uterine spasmodic pain and the improvement of sleep quality.关键词
曲马多/布托啡诺/静脉自控镇痛/子宫痉挛性疼痛Key words
Tramadol/Butorphanol/Patient-controlled intravenous analgesia/Uterine spasmodic pain分类
医药卫生引用本文复制引用
朱思佳,周新春,黎冰..曲马多联合布托啡诺对重复剖宫产术后子宫痉挛性疼痛的镇痛作用[J].中国医药科学,2025,15(2):53-56,4.基金项目
广东省惠州市医疗卫生领域科技计划项目(2022CZ010177). （2022CZ010177）
