摘要
Abstract
Objective:To investigate the related factors of severe neonatal respiratory distress syndrome(NRDS).Method:Clinical data of 171 children with NRDS admitted to Jiujiang Maternal and Child Health Hospital from January 2021 to August 2024 were retrospectively selected.According to the severity of the disease,children with severe NRDS were included in the severe group(n=50),and those with mild NRDS were included in the mild group(n=121).The data differences between the two groups were compared,and the items with statistical significance were included in the logistic regression analysis model for multi-factor analysis,and the risk factors for severe NRDS were screened.Result:There were statistically significant differences in gestational age,intrauterine infection,pregnancy complications/comorbidity,delivery mode,fetal intrauterine distress and postpartum pulmonary surfactant(PS)application between the two groups(P<0.05).There were no significant differences in gender,body weight,maternal birth time,age,adverse pregnancy history,prenatal corticosteroids and reproductive tract infection between the two groups(P>0.05).logistic regression analysis showed that gestational age<34 weeks,intrauterine infection,pregnancy complications/comorbidity,cesarean section,fetal intrauterine distress were the risk factors for severe NRDS(P<0.05),and postpartum PS use was the protective factor(P<0.05).Conclusion:The occurrence of severe NRDS is the result of multiple factors such as gestational age,intrauterine infection,pregnancy complications/comorbidity,delivery mode,fetal intrauterine distress and postpartum PS application,which should be paid attention to clinically.关键词
新生儿呼吸窘迫综合征/胎儿宫内窘迫/宫内感染Key words
Neonatal respiratory distress syndrome/Fetal intrauterine distress/Intrauterine infection