中国肿瘤生物治疗杂志2025，Vol.32Issue(1)：24-29,6.DOI:10.3872/j.issn.1007-385x.2025.01.004
免疫细胞介导的药物递送系统
Immune cell-mediated drug delivery system
摘要
Abstract
Immune cell-mediated delivery system employs immune cells as carriers to deliver therapeutic drugs to specific lesion sites by leveraging the innate chemotaxis of these cells.Due to its excellent biocompatibility,low immunogenicity,tissue-specific homing,and ability to cross biological barriers,this approach has emerged as an important strategy for drug delivery and disease treatment.This article systematically discusses the drug delivery strategies of immune cells,the biological characteristics,advantages,and disadvantages of using monocytes,neutrophils,mesenchymal stem cells,and dendritic cells as carrier cells,as well as the latest research progresses on their application in tumor treatment.This review provides valuable insights for further studies on immune cell-mediated drug delivery systems and their clinical transformation.关键词
免疫细胞/纳米药物/药物递送系统/靶向治疗/肿瘤Key words
immune cell/nanomedicine/drug delivery system/target therapy/tumor分类
临床医学引用本文复制引用
李从文,储以微..免疫细胞介导的药物递送系统[J].中国肿瘤生物治疗杂志,2025,32(1):24-29,6.基金项目
国家自然科学基金重点项目(No.82130050,No.82330053) （No.82130050,No.82330053）
