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Novel mouse model of Alzheimer's disease exhibits pathology through synergistic interactions among amyloid-β,tau,and reactive astrogliosis

Young-Eun Han Sunhwa Lim Seung Eun Lee Min-Ho Nam Soo-Jin Oh

动物学研究2025，Vol.46Issue(1)：41-53,13.

动物学研究2025，Vol.46Issue(1)：41-53,13.DOI:10.24272/j.issn.2095-8137.2024.257

Novel mouse model of Alzheimer's disease exhibits pathology through synergistic interactions among amyloid-β,tau,and reactive astrogliosis

Young-Eun Han ¹Sunhwa Lim ¹Seung Eun Lee ²Min-Ho Nam ¹Soo-Jin Oh¹

作者信息

1. Brain Science Institute,Korea Institute of Science and Technology(KIST),Seoul 02792,Republic of Korea
2. Research Animal Resources Center,Korea Institute of Science and Technology(KIST),Seoul 02792,Republic of Korea
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摘要

关键词

Alzheimer's disease mouse model/Neurofibrillary tangles/Amyloid-β plaques/Reactive astrogliosis/Alzheimer's disease pathology

Key words

Alzheimer's disease mouse model/Neurofibrillary tangles/Amyloid-β plaques/Reactive astrogliosis/Alzheimer's disease pathology

引用本文复制引用

Young-Eun Han,Sunhwa Lim,Seung Eun Lee,Min-Ho Nam,Soo-Jin Oh..Novel mouse model of Alzheimer's disease exhibits pathology through synergistic interactions among amyloid-β,tau,and reactive astrogliosis[J].动物学研究,2025,46(1):41-53,13.

基金项目

This study was supported by the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT & Future Planning(2022R1A2C2006229,2022R1A6A3A01086868),Korea Dementia Research Project through the Korea Dementia Research Center(KDRC)funded by the Ministry of Health & Welfare and Ministry of Science and ICT,Republic of Korea(RS-2024-00345328),and KIST Institutional Grant(2E32851) （NRF）

动物学研究

ISSN：0254-5853

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