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Elevated CXCL1 triggers dopaminergic neuronal loss in the substantia nigra of C57BL/6J mice:Evaluation of a novel Parkinsonian mouse model

Xi-Zhen Ma Guo-Rui Jia Meng-Yu Li Sheng-Han Zhang Zhao-Xin Wang Ning Song Ying-Juan Liu Jun-Xia Xie

动物学研究2025，Vol.46Issue(1)：225-235,11.

动物学研究2025，Vol.46Issue(1)：225-235,11.DOI:10.24272/j.issn.2095-8137.2024.228

Elevated CXCL1 triggers dopaminergic neuronal loss in the substantia nigra of C57BL/6J mice:Evaluation of a novel Parkinsonian mouse model

Xi-Zhen Ma ¹Guo-Rui Jia ²Meng-Yu Li ²Sheng-Han Zhang ²Zhao-Xin Wang ²Ning Song ²Ying-Juan Liu ²Jun-Xia Xie²

作者信息

1. Institute of Brain Science and Disease,School of Basic Medicine,Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders,Qingdao University,Qingdao,Shandong 266071,China||College of Life Sciences and Health,University of Health and Rehabilitation Science,Qingdao,Shandong 266113,China
2. Institute of Brain Science and Disease,School of Basic Medicine,Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders,Qingdao University,Qingdao,Shandong 266071,China
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摘要

关键词

Parkinson's disease/Mouse model/CXCL1/Inflammation/PPAR signaling pathway

Key words

Parkinson's disease/Mouse model/CXCL1/Inflammation/PPAR signaling pathway

引用本文复制引用

Xi-Zhen Ma,Guo-Rui Jia,Meng-Yu Li,Sheng-Han Zhang,Zhao-Xin Wang,Ning Song,Ying-Juan Liu,Jun-Xia Xie..Elevated CXCL1 triggers dopaminergic neuronal loss in the substantia nigra of C57BL/6J mice:Evaluation of a novel Parkinsonian mouse model[J].动物学研究,2025,46(1):225-235,11.

基金项目

This work was supported by the National Natural Science Foundation of China(32471049,32170984,32471188,32200802)and Natural Science Foundation of Shandong Province(ZR2023QH110) （32471049,32170984,32471188,32200802）

动物学研究

ISSN：0254-5853

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