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Advances and applications of genome-edited animal models for severe combined immunodeficiency

Xiao Zheng Chun-Hui Huang Sen Yan Ming-Deng Rong

动物学研究2025，Vol.46Issue(1)：249-260,12.

动物学研究2025，Vol.46Issue(1)：249-260,12.DOI:10.24272/j.issn.2095-8137.2024.195

Advances and applications of genome-edited animal models for severe combined immunodeficiency

Xiao Zheng ¹Chun-Hui Huang ²Sen Yan ³Ming-Deng Rong¹

作者信息

1. Stomatological Hospital,School of Stomatology,Southern Medical University,Guangzhou,Guangdong 510280,China
2. Guangdong Key Laboratory of Non-Human Primate Models,Guangdong-Hongkong-Macau Institute of CNS Regeneration,Jinan University,Guangzhou,Guangdong 510632,China||School of medicine,Jinan University,Guangzhou,Guangdong 510632,China
3. Guangdong Key Laboratory of Non-Human Primate Models,Guangdong-Hongkong-Macau Institute of CNS Regeneration,Jinan University,Guangzhou,Guangdong 510632,China||School of medicine,Jinan University,Guangzhou,Guangdong 510632,China||Department of Neurology,Guangzhou Red Cross Hospital,Faculty of Medical Science,Jinan University,Guangzhou,Guangdong 510220,China
折叠

摘要

关键词

Gene-editing technology/Animal model/Translational biomedicine/Severe combined immunodeficiency disease

Key words

Gene-editing technology/Animal model/Translational biomedicine/Severe combined immunodeficiency disease

引用本文复制引用

Xiao Zheng,Chun-Hui Huang,Sen Yan,Ming-Deng Rong..Advances and applications of genome-edited animal models for severe combined immunodeficiency[J].动物学研究,2025,46(1):249-260,12.

基金项目

This work was supported by the Postdoctoral Fellowship Program of CPSF(GZC20231064),China Postdoctoral Science Foundation(2024M761345),Guangzhou Basic and Applied Basic Research Foundation(2024A04J6615),Scientific Research Project of Southern Medical University Stomatological Hospital(PY2023004),National Key Research and Development Program of China(2021YFA0805300)and National Natural Science Foundation of China(82171244,32470564) （GZC20231064）

动物学研究

ISSN：0254-5853

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