康复学报2025,Vol.35Issue(1):1-10,10.DOI:10.3724/SP.J.1329.2025.01001
神经影像与电生理学证据揭秘意识障碍
Neuroimaging and Electrophysiology Evidence Unveiling the Mystery of Disorders of Consciousness
摘要
Abstract
As consciousness has always been an unsolved mystery for human beings,the diagnosis and prognosis of disorders of consciousness(DOC)after brain injury have also faced great challenges in clinical practice.Researchers and clinicians have been actively searching for clues from neuroimaging and electrophysiology to explore the biological and pathological mechanisms of hu-man consciousness and to provide new evidence for the neural basis of consciousness impairment and rehabilitation.Among them,neuroimaging techniques,including positron emission tomography(PET),functional magnetic resonance imaging(fMRI),and func-tional near-infrared spectroscopy(fNIRS),as well as electrophysiological techniques,including spontaneous electroencephalograms(EEG),event-related potentials(ERPs),and transcranial magnetic stimulation-induced electroencephalograms(TMS-EEG),have provided different dimensional features related to consciousness.These techniques have all somewhat advanced the clinical diagno-sis and prognosis of DOC,and are closely linked to DOC-related clinical practice,facilitating more scientific clinical management of DOC patients.关键词
意识障碍/人类意识/脑电图/功能性磁共振成像/经颅磁同步脑电Key words
disorders of consciousness/human consciousness/electroencephalograms/functional magnetic resonance imaging/transcranial magnetic stimulation-induced electroencephalograms引用本文复制引用
白洋..神经影像与电生理学证据揭秘意识障碍[J].康复学报,2025,35(1):1-10,10.基金项目
国家自然科学基金项目(82472605) (82472605)
江西省自然科学重点项目(20242BAB26155) (20242BAB26155)
江西省自然科学基金项目(20232ACB216007) (20232ACB216007)