分子影像学杂志2025，Vol.48Issue(2)：191-196,6.DOI:10.12122/j.issn.1674-4500.2025.02.10
区域性软脑膜侧支评分与动脉到达伪影评分评估患者脑功能状态的价值:基于3D TOF MRA与3D-ASL成像
Evaluation value of regional leptomeningeal collateral and arterial transit artifact scores in assessing brain function status of patients:based on 3D TOF MRA and 3D-ASL imaging
摘要
Abstract
Objective To explore the relationship between regional leptomeningeal collateral(rLMC)scoring assessed via three-dimensional time of flight magnetic resonance angiography(3D TOF MRA),arterial transit artifact(ATA)scoring obtained from three-dimensional arterial spin labeling(3D-ASL)imaging sequences,and cognitive impairment.Methods A retrospective analysis was conducted on 48 patients who underwent brain imaging,including T1WI,T2WI,T2 FLAIR,3D TOF MRA and 3D-ASL at Xiangya Hospital,Central South University,from January 2018 to October 2023.The rLMC and ATA scores were used to evaluate the status of leptomeningeal collaterals,while the patients'activities of daily living(ADL)scores served as reference indicators for assessing cognitive function.Statistical analyses were performed to evaluate the relationships among the three scores.Results There was a statistically significant difference in ADL scores among different rLMC grading groups(P<0.05).There was a significant difference between the ATA and ADL scores(P<0.05).Spearman's correlation coefficient analysis demonstrated a significant positive correlation between ATA and ADL scores(P<0.05).However,no significant difference was found between rLMC and ATA scores based on variance analysis(P>0.05).Conclusion Both rLMC and ATA scores can serve as important imaging indicators for assessing brain function impairment.A well-developed collateral circulation can have a positive impact on the patient's brain function.In particular,changes in secondary meningeal collateral circulation can be used to predict or evaluate the patient's brain function,with the aim of developing personalized treatment plans in clinical practice.关键词
软脑膜侧支循环/脑功能/磁共振血管成像/三维动脉自旋标记/动脉到达伪影评分Key words
dural collateral circulation/brain function/magnetic resonance angiography/three-dimensional arterial spin labeling/artery reached the false film score引用本文复制引用
何艺琳,邓耿颖,何念慈,宋诗倩,陈伟,张慧..区域性软脑膜侧支评分与动脉到达伪影评分评估患者脑功能状态的价值:基于3D TOF MRA与3D-ASL成像[J].分子影像学杂志,2025,48(2):191-196,6.基金项目
湖南省大学生创新创业训练计划(湘教通[2022]174号-一般项目-4629) （湘教通[2022]174号-一般项目-4629）
湖南省线下一流本科课程(湘教通[2021]322号) （湘教通[2021]322号）
