肝胆胰外科杂志2025，Vol.37Issue(2)：81-85,5.DOI:10.11952/j.issn.1007-1954.2025.02.002
转移性肝癌患者营养状况及影响因素分析
Nutritional status and influencing factors for patients with metastatic liver cancer
摘要
Abstract
Objective To investigate the nutritional status and influencing factors of patients with metastatic liver cancer,to analyze the nutrition-related biochemical indicators,in order to provide a theoretical basis for individualized nutritional support.Methods A total of 99 patients with metastatic liver cancer,who were admitted to the Third Affiliated Hospital of Naval Medical University from Nov.2023 to Feb.2024,were prospectively enrolled in this study.The Nutritional Risk Screening 2002(NRS 2002)was used to conduct the survey,and Logistic regression analysis was performed to identify factors associated with the nutritional risk.Results The incidence of the nutritional risk in 99 patients with metastatic liver cancer was 35.4%.Univariate analysis revealed significant associations between the nutritional risk and the patients'age,primary tumor type,grip strength,BMI,as well as blood levels of TP,ALB,PA,AST,HGB and RBP(P<0.05).Multivariate Logistic regression analysis indicated that older age(OR=0.175,95%CI 0.018 to 1.712,P=0.034),lower grip strength(OR=2.985,95%CI 1.170 to 8.564,P=0.040),lower BMI(OR=3.337,95%CI 3.123 to 6.922,P=0.021),lower blood ALB(OR=2.828,95%CI 0.209 to 38.255,P=0.038)and lower blood PA levels(OR=1.911,95%CI 2.917 to 14.081,P=0.008)were associated with a higher risk of malnutrition.Conclusion Medical staffs should screen patients with metastatic liver cancer for the nutritional risk,focusing on elderly patients with low grip strength.It is also important to monitor patients'BMI,serum ALB and PA levels,provide nutritional education,raise awareness of the hazards of the nutritional risk,improve self-health management awareness,as well as develop and implement individualized nutritional support for patients.关键词
转移性肝癌/营养风险筛查2002/营养相关指标/握力/身体质量指数/白蛋白/前白蛋白Key words
metastatic liver cancer/Nutritional Risk Screening 2002(NRS 2002)/nutrition-related indicators/grip strength/body mass index/albumin/prealbumin分类
临床医学引用本文复制引用
李晨琪,张克诚,谢祁羽,张丞林,刘阳,葛瑞良..转移性肝癌患者营养状况及影响因素分析[J].肝胆胰外科杂志,2025,37(2):81-85,5.基金项目
国家自然科学基金(52371146) （52371146）
上海市公共卫生研究专项青年项目(2024GKQ26) （2024GKQ26）
上海市"科技创新行动计划"启明星扬帆专项(24YF2758300) （24YF2758300）
嘉定区自然科学研究课题(JDKW-2024-0013). （JDKW-2024-0013）
