国家科学评论（英文版）2025，Vol.12Issue(2)：5-8,4.DOI:10.1093/nsr/nwae291
Multi-omics analysis reveals a novel NFE2L3 variant impairing choroidal vasculature development in high myopia and myopic maculopathy
Multi-omics analysis reveals a novel NFE2L3 variant impairing choroidal vasculature development in high myopia and myopic maculopathy
Jiangnan He 1Qijun Liao 2Haidong Zou 3Jianfeng Zhu 1Chenji Wang 4Xun Xu 3Luyao Ye 5Hannan Xu 6Huanjie Yang 7Juan Shen 8Menghan Li 6Shijun Weng 9Dongyue Jiao 4Chen Chu1
作者信息
- 1. Department of Preventative Ophthalmology,Shanghai Eye Diseases Prevention &Treatment Center/Shanghai Eye Hospital,School of Medicine,Tongji University,National Clinical Research Center for Eye Diseases,Shanghai Engineering Research Center of Precise Diagnosis and Treatment of Eye Diseases,China
- 2. BGI Research,China
- 3. Department of Preventative Ophthalmology,Shanghai Eye Diseases Prevention &Treatment Center/Shanghai Eye Hospital,School of Medicine,Tongji University,National Clinical Research Center for Eye Diseases,Shanghai Engineering Research Center of Precise Diagnosis and Treatment of Eye Diseases,China||Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Clinical Research Center for Eye Diseases,Shanghai Key Clinical Specialty,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine,China
- 4. State Key Laboratory of Genetic Engineering,MOE Engineering Research Center of Gene Technology,Shanghai Engineering Research Center of Industrial Microorganisms,School of Life Sciences,Fudan University,China
- 5. Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Clinical Research Center for Eye Diseases,Shanghai Key Clinical Specialty,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine,China||Department of Ophthalmology,The Affiliated People's Hospital of Ningbo University,China
- 6. Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai Clinical Research Center for Eye Diseases,Shanghai Key Clinical Specialty,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine,China
- 7. BGI Research,China||College of Life Sciences,University of Chinese Academy of Sciences,China
- 8. BGI Research,China||Institute of Metagenomics,Qingdao-Europe Advanced Institute for Life Sciences,BGI Research,China
- 9. State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Fudan University,China
- 折叠
引用本文复制引用
Jiangnan He,Qijun Liao,Haidong Zou,Jianfeng Zhu,Chenji Wang,Xun Xu,Luyao Ye,Hannan Xu,Huanjie Yang,Juan Shen,Menghan Li,Shijun Weng,Dongyue Jiao,Chen Chu..Multi-omics analysis reveals a novel NFE2L3 variant impairing choroidal vasculature development in high myopia and myopic maculopathy[J].国家科学评论（英文版）,2025,12(2):5-8,4.基金项目
This work was supported by the National Key Research and Development Program of China(2022YFC2502800,2019YFC0840607,2022YFA1104200 and 2022YFC2703102),Na-tional Natural Science Foundation of China(82171100,92357301,32370726,82304089 and 82401301),Natural Science Foundation of Shang-hai(23ZR1459200 and 22ZR1406600),Shanghai Key Disciplines to strengthen the construction of Public health system Three-year action Plan(2023-2025)(GWVI-11.1-22),Shanghai Shenkang Hospi-tal Clinical Research Program(SHDC12020127),Science and Technology Research Program of Shanghai(9DZ2282100),and China Postdoctoral Science Foundation(2024M752442).The spon-sors or funding organizations had no role in the design or conduct of this research. （2022YFC2502800,2019YFC0840607,2022YFA1104200 and 2022YFC2703102）
