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Cascade specific endogenous Fe3+interference and in situ catalysis for tumor therapy with stemness suppression

Jiajie Chen Chengtie Wu Jianlin Shi Yitong Wang Jian Huang Zhibo Yang Huicong Niu Xiaolian Su Jimin Huang Hongshi Ma Yufang Zhu

国家科学评论（英文版）2025，Vol.12Issue(2)：253-269,17.

国家科学评论（英文版）2025，Vol.12Issue(2)：253-269,17.DOI:10.1093/nsr/nwae434

Cascade specific endogenous Fe3+interference and in situ catalysis for tumor therapy with stemness suppression

Jiajie Chen ¹Chengtie Wu ¹Jianlin Shi ²Yitong Wang ³Jian Huang ⁴Zhibo Yang ¹Huicong Niu ⁵Xiaolian Su ³Jimin Huang ¹Hongshi Ma ¹Yufang Zhu¹

作者信息

1. State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China||Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,Beijing 100049,China
2. State Key Laboratory of High Performance Ceramics and Superfine Microstructure,Shanghai Institute of Ceramics,Chinese Academy of Sciences,Shanghai 200050,China||Center of Materials Science and Optoelectronics Engineering,University of Chinese Academy of Sciences,Beijing 100049,China||Shanghai Frontiers Science Center of Nanocatalytic Medicine,Shanghai Tenth People's Hospital,School of Medicine,Tongji University,Shanghai 200331,China
3. Department of Radiology,Shanghai Tenth People's Hospital,School of Medicine,Tongji University,Shanghai 200072,China
4. Materials Genome Institute,Shanghai University,Shanghai 200444,China
5. Department of Neurology,Minhang Hospital,Fudan University,Shanghai 200032,China
折叠

摘要

关键词

cancer stem-like cells/stemness inhibition/nanomedicine/endogenous Fe3+interference/catalytic therapy

Key words

cancer stem-like cells/stemness inhibition/nanomedicine/endogenous Fe3+interference/catalytic therapy

引用本文复制引用

Jiajie Chen,Chengtie Wu,Jianlin Shi,Yitong Wang,Jian Huang,Zhibo Yang,Huicong Niu,Xiaolian Su,Jimin Huang,Hongshi Ma,Yufang Zhu..Cascade specific endogenous Fe3+interference and in situ catalysis for tumor therapy with stemness suppression[J].国家科学评论（英文版）,2025,12(2):253-269,17.

基金项目

This work was supported by the National Key Research and De-velopment Program of China(2022YFB3804500),the Shanghai Pilot Program for Basic Research-Chinese Academy of Sciences,Shanghai Branch(JCYJ-SHFY-2022-003),the National Natu-ral Science Foundation of China(22335006 and 32101090),the China Postdoctoral Science Foundation(2024M763409),the Shanghai Rising-Star Project(Sailing Program)(24YF2753400),and the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(ZDBS-LY-SLH029). （2022YFB3804500）

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