中国实用神经疾病杂志2025，Vol.28Issue(4)：409-414,6.DOI:10.12083/SYSJ.240175
前循环大血管闭塞患者磁共振T2-FLAIR特征与侧支循环及溶栓治疗预后的相关性
Correlation between T2-FLAIR characteristics and collateral circulation and prognosis of thrombolytic therapy for patients with anterior circulation large vessel occlusion
摘要
Abstract
Objective To investigate the correlation between T2-fluid attenuated inversion recovery imaging(T2-FLAIR)characteristics and the collateral circulation and prognosis of thrombolytic therapy for patients with anterior circulation large vessel occlusion(LVO).Methods From January 2020 to March 2023,149 patients with anterior circulation LVO in the Yantaishan Hospital were selected as the research objects.All patients underwent MRI to obtain T2-FLAIR features,which were used to analyze the correlation between T2-FLAIR features and collateral circulation of patients with anterior circulation LVO.The included patients were divided into two groups according to their prognosis:good prognosis group and poor prognosis group.Logistic regression was used to analyze the correlation between T2-FLAIR characteristics of patients with anterior circulation LVO and the prognosis of thrombolytic therapy.Results During the 6-month follow-up of 149 patients after discharge,32 patients were included in the good prognosis group,and 117 patients were included in the poor prognosis group.Logistic regression analysis showed that NIHSS score at admission(OR=1.319),time from onset to treatment(OR=1.905),HVS classification(grade Ⅰ)(OR=0.044)and collateral circulation score(OR=0.421)were all related to the prognosis of patients with anterior circulation LVO after thrombolytic therapy(all P<0.05).After excluding other confounding factors,HVS classification was still significantly related to the prognosis of thrombolytic therapy in patients with anterior circulation LVO.The areas under ROC curve were 0.713,0.683,0.719 and 0.713,respectively.Spearman correlation coefficient analysis showed that HVS classification was positively correlated with collateral circulation score(r=0.442,P<0.001).Conclusion T2-FLAIR HVS classification of patients with anterior circulation LVO is significantly related to collateral circulation and prognosis of thrombolytic therapy,and can be used to evaluate collateral circulation and prognosis of patients with anterior circulation LVO.关键词
大血管闭塞/前循环/侧支循环/溶栓/T2液体衰减反转恢复序列/磁共振成像Key words
Large vessel occlusion/Anterior circulation/Collateral circulation/Thrombolysis/T2-fluid attenuated inversion recovery/Magnetic resonance imaging(MRI)分类
医药卫生引用本文复制引用
张磊,于敏,隋旭蕾..前循环大血管闭塞患者磁共振T2-FLAIR特征与侧支循环及溶栓治疗预后的相关性[J].中国实用神经疾病杂志,2025,28(4):409-414,6.基金项目
烟台市科技创新发展计划项目(编码:2021YD036) （编码:2021YD036）
