中国实用神经疾病杂志2025，Vol.28Issue(4)：514-519,6.DOI:10.12083/SYSJ.240455
昼夜节律紊乱与术后认知功能障碍的研究进展
Research progress of circadian rhythm disorder and postoperative cognitive dysfunction
摘要
Abstract
Postoperative cognitive dysfunction(POCD)is an urgent problem in the medical field,which is closely related to postoperative recovery,the length of hospital stay,and the quality of life for patients.In recent years,research on POCD has also been conducted in the field of genetics.The circadian rhythm,as a core regulatory mechanism supporting basic life activities,plays an indispensable role in regulating key functions,such as emotions and memory,and plays an important role in various disease progression and prognosis assessments,especially in cognitive aspects.The transcriptional translation loop of biological clock genes,as the molecular basis of circadian rhythms,has attracted the attention of many researchers.This article mainly reviews the relationship between circadian rhythm disorders and postoperative cognitive function,aiming to provide innovative prevention strategies and promising treatment targets for the prevention and treatment of POCD,in order to improve the postoperative recovery of patients.关键词
术后认知功能障碍/昼夜节律紊乱/生物钟基因/基因多态性/术后康复Key words
Postoperative cognitive dysfunction/Circadian rhythm disorder/Clock gene/Genetic polymorphism/Postoperative recovery分类
临床医学引用本文复制引用
胡雅茹,王晓冬,王莹,邱颐..昼夜节律紊乱与术后认知功能障碍的研究进展[J].中国实用神经疾病杂志,2025,28(4):514-519,6.基金项目
内蒙古自治区自然基金项目(编号:2023MS08023) （编号:2023MS08023）
内蒙古医科大学科技创新团队计划项目(编号:YKD2022TD032) （编号:YKD2022TD032）
内蒙古医科大学面上项目(编号:YKD2023MS009) （编号:YKD2023MS009）
