中医药导报2025，Vol.31Issue(2)：47-56,10.DOI:10.13862/j.cn43-1446/r.2025.02.009
人参煮散饮片与传统饮片中皂苷类成分的UHPLC-Q-Exactive Orbitrap MS比较分析
Comparative Analysis of Ginsenosides in Renshen(Ginseng)Boiling Powder and Renshen(Ginseng)Traditional Decoction Pieces Based on UHPLC-Q-Exactive Orbitrap MS
摘要
Abstract
Objective:To study the relative content changes of chemical components in the decoction process of renshen(ginseng)boiling powder and renshen(ginseng)traditional decoction pieces to provide a reference for the study and clinical application of boiling powder.Methods:A total of 3 batches of renshen(ginseng)tradi-tional decoction pieces were processed into boiling powder,and UHPLC-Q-Exactive Orbitrap high-resolution liquid mass spectrometry technique was used to screen and identify the saponins with significant changes in the decoction process.Results:A total of 70 ginsenosides were identified,including 4 compounds with peak area difference rate(ω)≥50％,26 compounds with 50％＞ω≥ 10％,and 28 compounds with 10％＞ω≥0％.The weighted results showed that 1.00 g renshen(ginseng)boiling powder was equivalent to 1.39 g traditional renshen(ginseng)pieces.Conclusion:The efficacy of renshen(ginseng)boiling powder is basically the same as that of traditional decoction pieces,but the boiling powder have higher dissolution rate of active ingredients,which can reduce the cost.关键词
人参/人参煮散/人参皂苷/对比分析Key words
renshen(ginseng)/renshen(ginseng)boiling powder/ginsenosides/comparative analysis分类
中医学引用本文复制引用
赵雪,张中磊,梁可欣,邓含秀,黄书腾,张如月,王少平,李宁,张加余..人参煮散饮片与传统饮片中皂苷类成分的UHPLC-Q-Exactive Orbitrap MS比较分析[J].中医药导报,2025,31(2):47-56,10.基金项目
山东省泰山学者青年专家项目(tsqn202103110) （tsqn202103110）
山东省青创人才引育计划——中药复杂体系作用模式解析研究创新团队(10073004) （10073004）
