中医药导报2025，Vol.31Issue(2)：71-74,4.DOI:10.13862/j.cn43-1446/r.2025.02.013
地龙散联合中药热奄包治疗血瘀型腰椎间盘突出症的疗效及其对血清炎症因子水平的影响
The Efficacy of Dilong Powder(地龙散)+Traditional Chinese Medicine Hot Compress Comprehensive Therapy in the Treatment of Lumbar Disc Herniation with Blood Stasis Type and Its Influence on Serum Pro-inflammatory Cytokine Levels
摘要
Abstract
Objective:To evaluate the efficacy of Dilong powder combined with traditional Chinese medicine hot compress comprehensive therapy for the blood stasis type lumbar disc herniation and its effects on serum pro-inflammatory cytokines levels.Methods:A total of 100 patients with blood stasis type lumbar disc herniation were randomly divided into two groups:control group(50 cases)and treatment group(50 cases).The control group received Celecoxib capsules combined with traditional Chinese medicine hot compress,while the treatment group received a combination of Dilong powder and traditional Chinese medicine hot compress therapy.Treatment was administered with each course lasting for 7 days,and two courses were conducted in total.The clinical efficacy of the two groups were compared,and the visual analogue scale(VAS)scores,Japanese Orthopaedic Association(JOA)scores,white blood cell(WBC),C-reactive protein(CRP),interleukin-6(IL-6),and tumor necrosis factor-alpha(TNF-α)levels of the patients before and after treatment were observed.Results:The total effective rate in the treatment group was 98.00％(49/50),while it was 78.00％(39/50)in the control group,the clinical efficacy of the treatment group was superior to that in the control group(P＜0.05).After treatment,the WBC,CRP,IL-6,and TNF-α levels of both groups were decreased(P＜0.05),and the inflammatory cytokines levels of the treatment group significantly were lower than those of the control group(P＜0.05).The VAS scores of both groups were dropped(P＜0.05),and the JOA score were raised(P＜0.05).The VAS scores of the treatment group were lower than those of the control group(P＜0.05),while the JOA scores of the treatment group were higher than those of the control group(P＜0.05).Conclusion:Com-bining Dilong powder with traditional Chinese medicine hot compress therapy can effectively improve clinical outcomes of blood stasis type lumbar disc herniation and reduce pro-inflammatory cytokines levels.关键词
腰椎间盘突出症/血瘀型:地龙散/中药热奄包/塞来昔布/炎症因子Key words
lumbar disc herniation/blood stasis type:Dilong Powder/traditional Chinese medicine hot compress/Celecoxib capsules/inflammatory cytokines分类
医药卫生引用本文复制引用
曾朝辉,文成,周全,杨超,尹增涓..地龙散联合中药热奄包治疗血瘀型腰椎间盘突出症的疗效及其对血清炎症因子水平的影响[J].中医药导报,2025,31(2):71-74,4.基金项目
湖南省中医药管理局项目(2022120) （2022120）
