激光生物学报2025，Vol.34Issue(1)：18-25,8.DOI:10.3969/j.issn.1007-7146.2025.01.003
肝癌三联检及高尔基体蛋白73在肝癌早期筛查中的作用及研究进展
The Role and Research Progress of the Liver Cancer Triple Test and Golgi Protein 73 in Early Liver Cancer Screening
摘要
Abstract
According to statistical data,hepatocellular carcinoma(HCC)is one of the most malignant cancers with high incidence and mortality rates,causing a severe burden on society.In response to the serious situation of HCC,the search for efficient early screening methods has become a research hotspot both domestically and internationally.This article reviews the main serum markers for HCC over the past five years,including alpha-fetoprotein(AFP),alpha-fetoprotein-L3 isoform ratio(AFP-L3%),des-gamma-carboxy prothrombin(DCP),and Golgi protein 73(GP73).It summarizes the advantages and limitations of these biomarkers and their role in combination with other indicators in the early screening of HCC,as well as the research progress.The article also proposes future development directions to assist in the diagnosis of HCC.关键词
肝癌/肝癌三联检/高尔基体蛋白73/早期筛查/诊断Key words
liver cancer/liver cancer triple test/GP73/early screening/diagnosis分类
临床医学引用本文复制引用
王聪,唐子华,姚红兵,向桢,周亚莉..肝癌三联检及高尔基体蛋白73在肝癌早期筛查中的作用及研究进展[J].激光生物学报,2025,34(1):18-25,8.基金项目
广西医疗卫生适宜技术开发与推广应用项目(S2021008) （S2021008）
国家自然科学基金项目(82160517). （82160517）
