中国当代医药2025，Vol.32Issue(5)：52-56,5.DOI:10.3969/j.issn.1674-4721.2025.05.11
急性非静脉曲张性上消化道出血患者痛风发作的影响因素分析
Analysis of the influencing factors of gout attacks in patients of acute non-variceal upper gastrointestinal bleeding
摘要
Abstract
Objective To explore the influencing factors of gout attacks in patients of acute non-variceal upper gastroin-testinal bleeding(ANVUGIB).Methods A total of 105 patients with ANVUGIB admitted to Suizhou Central Hospital from June 2018 to June 2022 were selected as the research objects.The patients were divided into gout attack group(29 cases)and gout non attack group(76 cases).Single factor regression and multi factor regression were applied to analyze the influencing factors of gout attacks.Results Single factor analysis result prompted that there were statistically significant dif-ferences in the comparison of levels of body mass index(BMI),blood biochemical indicator total cholesterol(TC)and triglycerides(TG)(P＜0.05).The results of multiple logistic regression analysis showed that,whether blood transfusion or not(β=0.218,OR=1.127,95％CI:1.013-1.296),whether combined use of Sodium Bicarbonate or not(β=0.374,OR=1.232,95％CI:0.913-1.384)、Omeprazole(β=0.283,OR=1.093,95％CI:0.728-1.138),Esomeprazole(β-0.103,OR=0.957,95％CI:0.649-1.264),uric acid level(β=0.329,OR=1.192,95％CI:0.925-1.296)were the independent influencing fac-tors for acute gout attacks in ANVUGIB(P＜0.05).Conclusion Whether blood transfusion or not,whether combined use of Sodium Bicarbonate or not,Omeprazole,Esomeprazole and uric acid level were the influencing factors for acute gout attacks in ANVUGIB.Understanding these factors,can better pre-vent gout attacks in patients with ANVUGIB.关键词
急性非静脉曲张性出血/碳酸氢钠/痛风/艾司奥美拉唑/体重指数Key words
Acute non-variceal hemorrhage/Sodium Bicarbonate/Gout/Esomeprazole/Body mass index分类
医药卫生引用本文复制引用
郭建超,陈志勇,周琳..急性非静脉曲张性上消化道出血患者痛风发作的影响因素分析[J].中国当代医药,2025,32(5):52-56,5.基金项目
湖北省随州市卫生健康委科研项目(2021SZ32022). （2021SZ32022）
