中国当代医药2025，Vol.32Issue(6)：27-30,4.DOI:10.3969/j.issn.1674-4721.2025.06.05
冠心病患者多支病变的预测因素分析
Analysis of predictive factors for multi-vessel disease in patients with coronary heart disease
摘要
Abstract
Objective To explore the predictive factors of multi-vessel disease in coronary heart disease.Methods A total of 143 patients with coronary artery disease admitted to the First Affiliated Hospital of Soochow University from January to March 2023 were selected as the study objects.According to the degree of coronary artery stenosis,they were divided into single-vessel disease group(62 cases)and multi-vessel disease group(81 cases).The clinical data of the two groups of patients were collected,the influencing factors of multi-vessel lesions were evaluated by multivariate logistic regression analysis,and the predictive factors of multi-vessel lesions were analyzed by ROC curve.Results There were significant dif-ferences in systolic blood pressure(SBP),diastolic blood pressure(DBP),drinking history,smoking history,history of percutaneous coronary intervention(PCI),blood uric acid,high density lipoprotein cholesterol(HDL-C)and apolipoprotein A1(ApoA1)between two groups(P＜0.05).Multivariate logistic regression analysis showed that smoking history(β=0.946,OR=2.575,95％CI:1.209-5.485),SBP(β=0.022,OR=1.023,95％CI:1.002-1.044)were independent risk factors for multi-vessel lesions,and HDL-C(β=-1.450,OR=0.235,95％CI:0.060-0.921)was independent protective factor.ROC analysis showed that both HDL-C and SBP had certain predictive value for multi-vessel lesions(AUC=0.610 and 0.633),and the combined effect of smoking,HDL-C and SBP on the prediction of multi-vessel disease was better than that of single index(AUC=0.688).Conclusion Smoking and SBP are risk factors for coronary heart disease,which should be observed in clinic.In addition,HDL-C and SBP have certain predictive value for the occurrence of multi-vessel disease in coronary heart disease.关键词
冠心病/多支病变/高密度脂蛋白胆固醇/收缩压/预测Key words
Coronary heart disease/Multi-vessel disease/High-density lipoprotein cholesterol/Systolic blood pressure/Prediction分类
临床医学引用本文复制引用
韩睿,潘婉倩,张宇祯,陈伟翔,蒋廷波..冠心病患者多支病变的预测因素分析[J].中国当代医药,2025,32(6):27-30,4.基金项目
国家自然科学基金(82370512) （82370512）
江苏省高等学校基础科学(自然科学)研究项目(23KJB320019). （自然科学）
