中国当代医药2025，Vol.32Issue(6)：40-44,5.DOI:10.3969/j.issn.1674-4721.2025.06.08
芪苈强心胶囊联合新四联方案治疗心力衰竭患者的临床效果
Clinical effect of Qili Qiangxin Capsules combined with new quadruple regimen in the treatment of patients with heart failure
摘要
Abstract
Objective To study the clinical effect of Qili Qiangxin Capsules combined with new quadruple regimen in the treatment of patients with heart failure.Methods A total of 90 patients with heart failure admitted to Jiujiang NO.1 People's Hospital from November 2021 to December 2022 were selected as the study objects,and they were divided into control group(45 cases)and study group(45 cases)according to random number table method.The control group was treated with angiotensin receptor-neprilysin inhibitor(ARNI)/angiotension converting enzyme inhibitor(ACEI)/angiotonin receptor blocker(ARB)+β-blocker+angiotonin receptor blocker(MRA)and other conventional regimens,while the study group was treated with Qili Qiangxin Capsules and Trimetazidine on the basis of the control group.The therapeutic effect,clinical indexes and renal function of the two groups were compared.Results The traditional Chinese medicine syndrome score of the study group was lower than that of the control group,and the therapeutic effect of traditional Chinese medicine syndrome score of the study group was better than that of the control group,the differences were statistically significant(P＜0.05).The total effective rate of cardiac function grade treatment in study group was higher than that in control group,the difference was statistically significant(P＜0.05).The serum N-terminal pro-brain natriuretic peptide(NT-proBNP)and brain natriuretic peptide(BNP)of the study group were lower than those of the control group,and the left ventricular ejection fraction(LVEF)and six-minute walking test(6MWT)of the study group were higher than those of the control group,with statistical significances(P＜0.05).Blood urea nitrogen(BUN)and serum creatinine(SCr)levels in study group were lower than those in control group,and estimated glomerular filtration rate(eGFR)level was higher than that in control group,with statistical significances(P＜0.05).Conclusion Qili Qiangxin Capsules combined with new quadruple regimen has a significant effect on the treatment of heart failure,which can actively improve the clinical symptoms and cardiac and renal function of patients,help patients to improve exercise tolerance,and is worthy of clinical promotion.关键词
心力衰竭/四联方案/芪苈强心胶囊/曲美他嗪/心功能/肾功能Key words
Heart failure/Quadruple regimen/Qili Qiangxin Capsules/Trimetazidine/Heart function/Renal function分类
医药卫生引用本文复制引用
柳万千,廖然..芪苈强心胶囊联合新四联方案治疗心力衰竭患者的临床效果[J].中国当代医药,2025,32(6):40-44,5.基金项目
江西省中医药管理局科技计划项目(2023B0569). （2023B0569）
