机器人外科学杂志（中英文）2025，Vol.6Issue(2)：251-255,5.DOI:10.12180/j.issn.2096-7721.2025.02.011
丙泊酚靶控输注麻醉与七氟烷吸入麻醉对机器人辅助腹腔镜下根治性前列腺切除术中患者脑氧代谢及认知功能的影响
Effects of propofol target-controlled infusion anaesthesia and sevoflurane inhalation anaesthesia on cerebral oxygen metabolism and cognitive function in patients undergoing robot-assisted laparoscopic radical prostatectomy
摘要
Abstract
Objective:To Explore the effects of propofol target-controlled infusion anesthesia and sevoflurane inhalation anesthesia on cerebral oxygen metabolism and cognitive function in patients undergoing robot-assisted laparoscopic radical prostatectomy(RARP).Methods:122 patients who underwent RARP from February 2021 to August 2023 in Xi'an International Medical Center Hospital were selected and divided into the study group(n=61,propofol target-controlled infusion anesthesia)and the control group(n=61,sevoflurane inhalation anesthesia)using a random number table.The recovery indicators,cerebral oxygen saturation,cognitive function(MMSE score),and adverse reactions were compared between the two groups of patients.Results:The respiratory recovery time,eye-opening time,and extubation time were lower in the study group than those in the control group(P＜0.05).Compared with that before induction,cerebral oxygen saturation was both decreased in the two groups during oxygenation,5 minutes after induction,during and after surgery(P＜0.05),while the cerebral oxygen saturation in the study group was higher than that in the control group at the time of during and after surgery,and eye-opening(P＜0.05).Compared with that before induction,MMSE scores at eye-opening and 1 day after surgery were both decreased in the two groups(P＜0.05),but they were relatively higher in the study group(P＜0.05).There was no statistically significant difference in the complication rates between the two groups(P＜0.05).Conclusion:The application of propofol target-controlled infusion anesthesia in patients undergoing RARP radical prostatectomy can effectively and safely maintain normal cerebral oxygen saturation,promote postoperative recovery,reduce its impact on cognitive function.关键词
根治性前列腺切除术/机器人辅助手术/丙泊酚靶控输注麻醉/七氟烷吸入麻醉Key words
Radical Prostatectomy/Robot-assisted Surgery/Propofol Target-controlled Infusion Anaesthesia/Sevoflurane Inhalation Anaesthesia分类
医药卫生引用本文复制引用
商燕,梁静,吕玉珠,王彬荣,柴伟,李艳..丙泊酚靶控输注麻醉与七氟烷吸入麻醉对机器人辅助腹腔镜下根治性前列腺切除术中患者脑氧代谢及认知功能的影响[J].机器人外科学杂志（中英文）,2025,6(2):251-255,5.基金项目
陕西省重点研发计划项目(2022SF-487) Key R&D Plan Project of Shaanxi Province(2022SF-487) （2022SF-487）
